Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide
Aperçu rapide pour Src Homology 2 Domain Containing Adaptor Protein B (SHB) Peptide (ABIN938096)
Antigène
Origine
Source
Application
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Type de proteíne
- Synthetic
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Séquence
- ERPSQPPQAV PQASSAASAS CGPATASCFS ASSGSLPDDS GSTSDLIRAY
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Attributs du produit
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A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody,
Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP.8 Blocking Peptide, bA3J10.2 Blocking Peptide
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Indications d'application
- Optimal conditions should be determined by the investigator
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
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Buffer
- PBS
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20 °C long term.
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- SHB (Src Homology 2 Domain Containing Adaptor Protein B (SHB))
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Sujet
- SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.
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Poids moléculaire
- 55 kDa
Antigène
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