A synthetic peptide for use as a blocking control in assays to test for specificity of SHB antibody, Alternative Names: SHB control peptide, SHB antibody Blocking Peptide, Anti-SHB Blocking Peptide, Src Homology 2 Domain Containing Adaptor Protein B Blocking Peptide, RP11-3J10.8 Blocking Peptide, bA3J10.2 Blocking Peptide
SHB
Reactivité: Humain, Souris, Rat
Hôte: Synthetic
BP
Indications d'application
Optimal conditions should be determined by the investigator
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Add 100 µL of distilled water for a final peptide concentration is 1 mg/mL.
Buffer
PBS
Conseil sur la manipulation
Avoid repeated freeze/thaw cycles.
Stock
-20 °C
Stockage commentaire
Store at -20 °C long term.
Antigène
SHB
(Src Homology 2 Domain Containing Adaptor Protein B (SHB))
Synonymes
SHB Peptide, RP11-3J10.8 Peptide, bA3J10.2 Peptide, RGD1565350 Peptide, BC028832 Peptide, SH2 domain containing adaptor protein B Peptide, src homology 2 domain-containing transforming protein B Peptide, SHB Peptide, Shb Peptide
Sujet
SHB is the adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. SHB may play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. SHB may also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. SHB may also regulate IRS1 and IRS2 signaling in insulin-producing cells.