PIK3R5 Produits
(Phosphoinositide-3-Kinase, Regulatory Subunit 5 (PIK3R5))
Catégories
Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011].
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Catégories PIK3R5 en vedette
PIK3R5 Anticorps
High quality antibodies with extensive validation data.
PIK3R5 Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PIK3R5 recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (6)
N° du produit
ABIN1500211
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Dog, Human, Monkey, Mouse, Rat
Application
WB, IHC, IF, IHC (p)
Validations
- (6)
N° du produit
ABIN1500212
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, IHC (p), FACS
Validations
- (3)
N° du produit
ABIN655491
Quantité
400 μL
Fiche technique
Fiche technique
PIK3R5 recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1315090
Quantité
25 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3094632
Quantité
1 mg
Fiche technique
Fiche technique
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
- (1)
N° du produit
ABIN3135235
Quantité
1 mg
Fiche technique
Fiche technique
Dernières publications sur nos produits PIK3R5
: "Genetic Profiles Associated with Chemoresistance in Patient-Derived Xenograft Models of Ovarian Cancer." dans: Cancer research and treatment : official journal of Korean Cancer Association, (2018) (PubMed).: "A missense mutation in PIK3R5 gene in a family with ataxia and oculomotor apraxia." dans: Human mutation, Vol. 33, Issue 2, pp. 351-4, (2012) (PubMed).
: "Roles of G beta gamma in membrane recruitment and activation of p110 gamma/p101 phosphoinositide 3-kinase gamma." dans: The Journal of cell biology, Vol. 160, Issue 1, pp. 89-99, (2003) (PubMed).
: "Inhibition of G1 cyclin-dependent kinase activity during growth arrest of human breast carcinoma cells by prostaglandin A2." dans: Molecular and cellular biology, Vol. 16, Issue 3, pp. 762-70, (1996) (PubMed).
: "Interleukin-2-mediated elimination of the p27Kip1 cyclin-dependent kinase inhibitor prevented by rapamycin." dans: Nature, Vol. 372, Issue 6506, pp. 570-3, (1995) (PubMed).
: "p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest." dans: Genes & development, Vol. 8, Issue 1, pp. 9-22, (1994) (PubMed).
Synonymes et noms alternatifs relatifs à PIK3R5
phosphoinositide-3-kinase regulatory subunit 5 (PIK3R5), phosphoinositide-3-kinase regulatory subunit 5 S homeolog (pik3r5.S), phosphoinositide-3-kinase, regulatory subunit 5 (Pik3r5), phosphoinositide-3-kinase regulatory subunit 5 (Pik3r5), AV230647, F730038I15Rik, FOAP-2, p101, P101, P101-PI3K, RGD1563261Protein level used designations for PIK3R5
- PI3-kinase regulatory subunit 5
- phosphoinositide-3-kinase, regulatory subunit 5, p101
- PI3-kinase p101 subunit
- phosphatidylinositol 4,5-bisphosphate 3-kinase regulatory subunit
- phosphatidylinositol-4,5-bisphosphate 3-kinase regulatory subunit
- phosphoinositide 3-kinase regulatory subunit 5
- protein FOAP-2
- ptdIns-3-kinase p101
- Phosphoinositide 3-kinase regulatory subunit 5
- IB PI3-kinase p101 subunit
- p101-PI3K
- ptdIns-3-kinase regulatory subunit
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