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PIM1 Produits

(Pim-1 Oncogene (PIM1))
The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).[provided by RefSeq, Aug 2011].

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Catégories PIM1 en vedette

PIM1 Anticorps

High quality antibodies with extensive validation data.

PIM1 Kits ELISA

Reliable ELISA kits for a wide range of species.

PIM1 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PIM1 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (4)
N° du produit ABIN7429160
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IF
Validations
  • (4)
N° du produit ABIN562235
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC
Validations
  • (4)
N° du produit ABIN7269375
Quantité 100 μL
Fiche technique Fiche technique

PIM1 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6958588
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380319
Quantité 2 x 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
N° du produit ABIN1503732
Quantité 96 tests
Fiche technique Fiche technique

PIM1 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Insect cells (Sf21)
Validations
  • (2)
N° du produit ABIN5570464
Quantité 5 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect cells (Sf9)
Validations
  • (2)
N° du produit ABIN5570463
Quantité 100 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124452
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PIM1

Xu, Xiong, Cao, Huang, Wang, You, Zhou, Zheng, Hu, Zhang, Zhao: "PIM-1 contributes to the malignancy of pancreatic cancer and displays diagnostic and prognostic value." dans: Journal of experimental & clinical cancer research : CR, Vol. 35, Issue 1, pp. 133, (2017) (PubMed).

Albertson, Schmidt, Bearss, Tripp, Bearss, Liu: "Patterns and Significance of PIM Kinases in Urothelial Carcinoma." dans: Applied immunohistochemistry & molecular morphology : AIMM, Vol. 23, Issue 10, pp. 717-23, (2016) (PubMed).

Wu, Lu, He, Jin: "PIM1 polymorphism and PIM1 expression as predisposing factors of esophageal squamous cell carcinoma in the Asian population." dans: OncoTargets and therapy, Vol. 9, pp. 2919-25, (2016) (PubMed).

Plum, Warnecke-Eberz, Dhaouadi, Alakus, Drebber, Metzger, Prenzel, Hölscher, Bollschweiler: "Molecular markers predicting lymph node metastasis in early esophageal cancer." dans: Histology and histopathology, pp. 11618, (2015) (PubMed).

Herzog, Fink, Weitmann, Friedel, Hadlich, Langner, Kindermann, Holm, Böhm, Eskilsson, Miletic, Hildner, Fritsch, Vogelgesang, Havemann, Ritter, Meyer zu Schwabedissen, Rauch, Hoffmann, Kroemer et al.: "Pim1 kinase is upregulated in glioblastoma multiforme and mediates tumor cell survival. ..." dans: Neuro-oncology, Vol. 17, Issue 2, pp. 223-42, (2015) (PubMed).

Egli, Zajonz, Burger, Schweighoffer: "Human CD180 Transmits Signals via the PIM-1L Kinase." dans: PLoS ONE, Vol. 10, Issue 11, pp. e0142741, (2015) (PubMed).

Menter, Ernst, Drachneris, Dirnhofer, Barghorn, Went, Tzankov: "Phenotype profiling of primary testicular diffuse large B-cell lymphomas." dans: Hematological oncology, Vol. 32, Issue 2, pp. 72-81, (2014) (PubMed).

Renard, Paulin, Breuils-Bonnet, Simard, Pibarot, Bonnet, Provencher: "Pim-1: A new biomarker in pulmonary arterial hypertension." dans: Pulmonary circulation, Vol. 3, Issue 1, pp. 74-81, (2013) (PubMed).

Ha, Iqbal, Mita, Ruoff, Gerald, Lepor, Taneja, Lee, Melamed, Garabedian, Logan: "Phosphorylation of the androgen receptor by PIM1 in hormone refractory prostate cancer." dans: Oncogene, Vol. 32, Issue 34, pp. 3992-4000, (2013) (PubMed).

Baron, Anastasi, Hyjek, Bies, Reddy, Dong, Joseph, Thirman, Wroblewski, Wolff, Baron: "PIM1 gene cooperates with human BCL6 gene to promote the development of lymphomas." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 15, pp. 5735-9, (2012) (PubMed).

Synonymes et noms alternatifs relatifs à PIM1

Pim-1 proto-oncogene, serine/threonine kinase (PIM1), proviral integration site 1 (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (Pim1), Pim-1 proto-oncogene, serine/threonine kinase (pim1), Pim-1 proto-oncogene, serine/threonine kinase L homeolog (pim1.L), PIM, pim, Pim-1, pim-1, PIM1, pim3

Protein level used designations for PIM1

  • Oncogene PIM1
  • pim-1 kinase 44 kDa isoform
  • pim-1 oncogene (proviral integration site 1)
  • proto-oncogene serine/threonine-protein kinase pim-1
  • serine/threonine-protein kinase pim-1
  • pim-1 oncogene
  • non-specific serine/threonine protein kinase
  • proto-oncogene serine/threonine-protein kinase Pim-1
  • proviral integration site 1
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