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PKC beta Produits

(Protein Kinase C, beta (PRKCB))

Catégories

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008].

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Catégories PKC beta en vedette

PKC beta Anticorps

High quality antibodies with extensive validation data.

PKC beta Kits ELISA

Reliable ELISA kits for a wide range of species.

PKC beta Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKC beta recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Application IHC, IF
Validations
  • (5)
N° du produit ABIN7257238
Quantité 200 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IF
Validations
  • (5)
N° du produit ABIN6146199
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Monkey, Mouse, Primate, Rat
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (3)
N° du produit ABIN545457
Quantité 400 μL
Fiche technique Fiche technique

PKC beta recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human, Mouse, Rat
Analytical Method Qualitative Cell ELISA
Validations
N° du produit ABIN1380789
Quantité 2 x 96 tests
Fiche technique Fiche technique

PKC beta recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316257
Quantité 25 μg
Fiche technique Fiche technique
Reactivity Human
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3093479
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Insect Cells
Validations
  • (1)
N° du produit ABIN3134607
Quantité 1 mg
Fiche technique Fiche technique

Dernières publications sur nos produits PKC beta

Kuai, Luo, Qu, Ru, Luo, Ding, Xing, Liu, Sun, Li, Li: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." dans: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).

Dobrikov, Dobrikova, Gromeier: "Ribosomal RACK1:Protein Kinase C βII Modulates Intramolecular Interactions between Unstructured Regions of Eukaryotic Initiation Factor 4G (eIF4G) That Control eIF4E and eIF3 Binding." dans: Molecular and cellular biology, Vol. 38, Issue 19, (2018) (PubMed).

Gan, Wang, Zhao, Wu, Yang, Peng: "5-(Bis(3-(2-hydroxyethyl)-1H-indol-2-yl)methyl)-2-hydroxybenzoic acid (BHIMHA): showing a strategy of designing drug to block lung metastasis of tumors." dans: Drug design, development and therapy, Vol. 10, pp. 711-21, (2016) (PubMed).

Wang, Qin, Deng, Yao: "Different localization and expression of protein kinase C-beta in kidney cortex of diabetic nephropathy mice and its role in telmisartan treatment." dans: American journal of translational research, Vol. 7, Issue 6, pp. 1116-25, (2015) (PubMed).

Nakura, Higuchi, Yoshida, Yoshikawa: "PKC? suppresses osteoblastic differentiation." dans: Bone, Vol. 48, Issue 3, pp. 476-84, (2011) (PubMed).

Fu, Deng, Zhao, Li, Zhou, Zhang: "Distinct expression patterns of hedgehog ligands between cultured and primary colorectal cancers are associated with aberrant methylation of their promoters." dans: Molecular and cellular biochemistry, Vol. 337, Issue 1-2, pp. 185-92, (2010) (PubMed).

Losso, Truax, Richard: "trans-resveratrol inhibits hyperglycemia-induced inflammation and connexin downregulation in retinal pigment epithelial cells." dans: Journal of agricultural and food chemistry, Vol. 58, Issue 14, pp. 8246-52, (2010) (PubMed).

Zhang, Major, Takanashi, Camp, Nishiya, Peters, Ginsberg, Jian, Randazzo, Schultz, Moon, Ding: "Small-molecule synergist of the Wnt/beta-catenin signaling pathway." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 18, pp. 7444-8, (2007) (PubMed).

Robertson, Kahl, Vose, de Vos, Laughlin, Flynn, Rowland, Cruz, Goldberg, Musib, Darstein, Enas, Kutok, Aster, Neuberg, Savage, LaCasce, Thornton, Slapak, Shipp: "Phase II study of enzastaurin, a protein kinase C beta inhibitor, in patients with relapsed or refractory diffuse large B-cell lymphoma." dans: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 25, Issue 13, pp. 1741-6, (2007) (PubMed).

Maines, Miralem, Lerner-Marmarosh, Shen, Gibbs: "Human biliverdin reductase, a previously unknown activator of protein kinase C betaII." dans: The Journal of biological chemistry, Vol. 282, Issue 11, pp. 8110-22, (2007) (PubMed).

Synonymes et noms alternatifs relatifs à PKC beta

protein kinase C beta (PRKCB), protein kinase C, beta (Prkcb), protein kinase C, beta b (prkcbb), protein kinase C, beta a (prkcba), A130082F03Rik, PKC, PKC-B, PKC-beta, PKC-Beta, Pkc53E, PKCB, Pkcb, Prkcb, PRKCB1, Prkcb1, prkcb1, prkcb1l, PRKCB2, Prkcb2, PRKCB_tv2, zgc:63591, zgc:64063

Protein level used designations for PKC beta

  • PKC-B
  • protein kinase C beta type
  • protein kinase C, beta 1 polypeptide
  • protein kinase C beta-II
  • protein kinase C, beta 1
  • PKC-beta
  • protein kinase C beta I
  • protein kinase C beta II
  • protein kinase C beta 1
  • protein kinase C, beta
  • protein kinase C beta 2
  • protein kinase C, beta 1, like
  • protein kinase C, beta a
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