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PKD2 Produits

(Protein Kinase D2 (PKD2))

Catégories

The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

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Catégories PKD2 en vedette

PKD2 Anticorps

High quality antibodies with extensive validation data.

PKD2 Kits ELISA

Reliable ELISA kits for a wide range of species.

PKD2 Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PKD2 recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, IHC (p), IF, IP, ICC
Validations
  • (6)
N° du produit ABIN2855325
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
N° du produit ABIN565195
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Dog, Human, Monkey, Rat
Application WB, IF, FACS
Validations
  • (4)
N° du produit ABIN1500413
Quantité 100 μL
Fiche technique Fiche technique

PKD2 recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116796
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116794
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN1116795
Quantité 96 tests
Fiche technique Fiche technique

PKD2 recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316288
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1316286
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Baculovirus infected Insect Cells
Validations
  • (1)
N° du produit ABIN7317066
Quantité 50 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PKD2

Zheng, Qian, Varghese, Baker, Fuchs: "Ligand-stimulated downregulation of the alpha interferon receptor: role of protein kinase D2." dans: Molecular and cellular biology, Vol. 31, Issue 4, pp. 710-20, (2011) (PubMed).

Azoitei, Kleger, Schoo, Thal, Brunner, Pusapati, Filatova, Genze, Möller, Acker, Kuefer, Van Lint, Baust, Adler, Seufferlein: "Protein kinase D2 is a novel regulator of glioblastoma growth and tumor formation." dans: Neuro-oncology, Vol. 13, Issue 7, pp. 710-24, (2011) (PubMed).

Zheng, Qian, Baker, Fuchs: "Tyrosine phosphorylation of protein kinase D2 mediates ligand-inducible elimination of the Type 1 interferon receptor." dans: The Journal of biological chemistry, Vol. 286, Issue 41, pp. 35733-41, (2011) (PubMed).

Pusapati, Krndija, Armacki, von Wichert, von Blume, Malhotra, Adler, Seufferlein: "Role of the second cysteine-rich domain and Pro275 in protein kinase D2 interaction with ADP-ribosylation factor 1, trans-Golgi network recruitment, and protein transport." dans: Molecular biology of the cell, Vol. 21, Issue 6, pp. 1011-22, (2010) (PubMed).

Liu, Evans, Britton, Zachary: "The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis." dans: Oncogene, Vol. 27, Issue 21, pp. 2989-98, (2008) (PubMed).

Sharlow, Giridhar, LaValle, Chen, Leimgruber, Barrett, Bravo-Altamirano, Wipf, Lazo, Wang: "Potent and selective disruption of protein kinase D functionality by a benzoxoloazepinolone." dans: The Journal of biological chemistry, Vol. 283, Issue 48, pp. 33516-26, (2008) (PubMed).

Yuan, Lugea, Zheng, Gukovsky, Edderkaoui, Rozengurt, Pandol: "Protein kinase D1 mediates NF-kappaB activation induced by cholecystokinin and cholinergic signaling in pancreatic acinar cells." dans: American journal of physiology. Gastrointestinal and liver physiology, Vol. 295, Issue 6, pp. G1190-201, (2008) (PubMed).

Bossard, Bresson, Polishchuk, Malhotra: "Dimeric PKD regulates membrane fission to form transport carriers at the TGN." dans: The Journal of cell biology, Vol. 179, Issue 6, pp. 1123-31, (2007) (PubMed).

Yeaman, Ayala, Wright, Bard, Bossard, Ang, Maeda, Seufferlein, Mellman, Nelson, Malhotra: "Protein kinase D regulates basolateral membrane protein exit from trans-Golgi network." dans: Nature cell biology, Vol. 6, Issue 2, pp. 106-12, (2004) (PubMed).

Rey, Yuan, Rozengurt: "Intracellular redistribution of protein kinase D2 in response to G-protein-coupled receptor agonists." dans: Biochemical and biophysical research communications, Vol. 302, Issue 4, pp. 817-24, (2003) (PubMed).

Synonymes et noms alternatifs relatifs à PKD2

protein kinase D2 (PRKD2), protein kinase D2 (Prkd2), serine/threonine-protein kinase D2 (LOC100407181), AI325941, nPKC-D2, PKD2, PRKD2, RGD1308054

Protein level used designations for PKD2

  • serine/threonine-protein kinase D2
  • nPKC-D2
  • protein kinase D2
  • serine/threonine-protein kinase D2-like
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