PKC zeta Produits
(Protein Kinase C, zeta (PRKCZ))
Catégories
Protein kinase C (PKC) zeta is a member of the PKC family of serine/threonine kinases which are involved in a variety of cellular processes such as proliferation, differentiation and secretion. Unlike the classical PKC isoenzymes which are calcium-dependent, PKC zeta exhibits a kinase activity which is independent of calcium and diacylglycerol but not of phosphatidylserine. Furthermore, it is insensitive to typical PKC inhibitors and cannot be activated by phorbol ester. Unlike the classical PKC isoenzymes, it has only a single zinc finger module. These structural and biochemical properties indicate that the zeta subspecies is related to, but distinct from other isoenzymes of PKC. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Catégories PKC zeta en vedette
PKC zeta Anticorps
High quality antibodies with extensive validation data.
PKC zeta Kits ELISA
Reliable ELISA kits for a wide range of species.
PKC zeta Protéines
Proteins for various applications incl. WB, ELISA, IF etc.
PKC zeta recommandé Anticorps
Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
N° du produit
ABIN6264247
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
N° du produit
ABIN6256558
Quantité
100 μL
Fiche technique
Fiche technique
Reactivity
Human
Application
WB, ELISA, RNAi
Validations
- (4)
N° du produit
ABIN562397
Quantité
100 μg
Fiche technique
Fiche technique
PKC zeta recommandé Kits ELISA
Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969724
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6969723
Quantité
96 tests
Fiche technique
Fiche technique
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
N° du produit
ABIN6958931
Quantité
96 tests
Fiche technique
Fiche technique
PKC zeta recommandé Protéines
Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity
Human
Source
Insect cells (Sf9)
Validations
- (2)
N° du produit
ABIN5570094
Quantité
100 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
N° du produit
ABIN7124655
Quantité
50 μg
Fiche technique
Fiche technique
Reactivity
Human
Source
Wheat germ
Validations
- (1)
N° du produit
ABIN1316280
Quantité
10 μg
Fiche technique
Fiche technique
Dernières publications sur nos produits PKC zeta
: "PKCζ in prostate cancer cells represses the recruitment and M2 polarization of macrophages in the prostate cancer microenvironment." dans: Tumour biology, Vol. 39, Issue 6, pp. 1010428317701442, (2017) (PubMed).: "Metabolic maintenance of cell asymmetry following division in activated T lymphocytes." dans: Nature, Vol. 532, Issue 7599, pp. 389-93, (2016) (PubMed).
: "Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota." dans: Cancer research, Vol. 68, Issue 18, pp. 7403-8, (2008) (PubMed).
: "Regulation of TNF-alpha-activated PKC-zeta signaling by the human biliverdin reductase: identification of activating and inhibitory domains of the reductase." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 21, Issue 14, pp. 3949-62, (2007) (PubMed).
: "Effects on ligand interaction and membrane translocation of the positively charged arginine residues situated along the C1 domain binding cleft in the atypical protein kinase C isoforms." dans: The Journal of biological chemistry, Vol. 281, Issue 44, pp. 33773-88, (2006) (PubMed).
: "Protein kinase Czeta (PKCzeta): activation mechanisms and cellular functions." dans: Journal of biochemistry, Vol. 133, Issue 1, pp. 1-7, (2003) (PubMed).
: "Activation and substrate specificity of the human protein kinase C alpha and zeta isoenzymes." dans: European journal of biochemistry / FEBS, Vol. 216, Issue 2, pp. 597-606, (1993) (PubMed).
: "The cDNA sequence encoding human protein kinase C-zeta." dans: Gene, Vol. 132, Issue 2, pp. 305-6, (1993) (PubMed).
Synonymes et noms alternatifs relatifs à PKC zeta
protein kinase C zeta L homeolog (prkcz.L), protein kinase C zeta (PRKCZ), protein kinase C zeta (prkcz), protein kinase C, zeta (PRKCZ), protein kinase C, zeta (Prkcz), protein kinase C zeta (Prkcz), protein kinase C, zeta (prkcz), 14-3-3-zetaisoform, AI098070, aPKCzeta, C80388, pkc-zeta, PKC-ZETA, pkc2, PKC2, Pkcz, pkcz, PKCzeta, PRKCZ, prkcz-A, r14-3-3, R74924, si:ch211-150o23.4, TPKC, zetaPKCProtein level used designations for PKC zeta
- protein kinase C, zeta
- protein kinase c type Z
- protein kinase C zeta type
- protein kinase C zeta type-like
- nPKC-zeta
- atypical protein kinase C
- protein kinase C zeta subspecies
- 14 - 3 - 3 - zeta isoform
- atypical protein kinase C zeta
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