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PPARGC1B Produits

(Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Catégories

The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010].

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Catégories PPARGC1B en vedette

PPARGC1B Anticorps

High quality antibodies with extensive validation data.

PPARGC1B Kits ELISA

Reliable ELISA kits for a wide range of species.

PPARGC1B recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
  • (1)
  • (3)
N° du produit ABIN872354
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, ELISA, FACS
Validations
  • (4)
N° du produit ABIN2683008
Quantité 0.1 mg
Fiche technique Fiche technique
Reactivity Human
Application ELISA, IHC
Validations
  • (2)
N° du produit ABIN7243736
Quantité 200 μL
Fiche technique Fiche technique

PPARGC1B recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN4993641
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
N° du produit ABIN6220445
Quantité 96 tests
Fiche technique Fiche technique

PPARGC1B recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3094725
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
  • (1)
N° du produit ABIN3136747
Quantité 1 mg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505260
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PPARGC1B

Chang, Lee, Lee, Park, Chung, Park: "Functional Characterization of Exonic Variants of the PPARGC1B Gene in Coregulation of Estrogen Receptor Alpha." dans: DNA and cell biology, Vol. 35, Issue 7, pp. 314-21, (2016) (PubMed).

Stevens, Lee, Kang, Lee, Lee, Bower, Jiang, Kang, Andrabi, Dawson, Shin, Dawson: "Parkin loss leads to PARIS-dependent declines in mitochondrial mass and respiration." dans: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 37, pp. 11696-701, (2015) (PubMed).

Zhou, Ma, Mo, Zheng, Chen, Wei, Dai et al.: "Down-regulating peroxisome proliferator-activated receptor-gamma coactivator-1 beta alleviates the proinflammatory effect of rheumatoid arthritis fibroblast-like synoviocytes through inhibiting ..." dans: Arthritis research & therapy, Vol. 16, Issue 5, pp. 472, (2015) (PubMed).

Lou, Zhang, Lucchinetti, Heck, Affolter, Gandhi, Kienesberger, Hersberger, Clanachan, Zaugg: "Infarct-remodelled hearts with limited oxidative capacity boost fatty acid oxidation after conditioning against ischaemia/reperfusion injury." dans: Cardiovascular research, Vol. 97, Issue 2, pp. 251-61, (2013) (PubMed).

Kemper, Zhao, Duckles, Krause: "Endogenous ovarian hormones affect mitochondrial efficiency in cerebral endothelium via distinct regulation of PGC-1 isoforms." dans: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 33, Issue 1, pp. 122-8, (2013) (PubMed).

Kammerer, Gutzwiller, Stauffer, Delhon, Seltenmeyer, Fournier: "Estrogen Receptor α (ERα) and Estrogen Related Receptor α (ERRα) are both transcriptional regulators of the Runx2-I isoform." dans: Molecular and cellular endocrinology, Vol. 369, Issue 1-2, pp. 150-60, (2013) (PubMed).

Liu, Zhou, Zhang, Tu, Xia, Wang, Zhou, Zhang, Wu, Gao, He, Zhai: "Liver Patt1 deficiency protects male mice from age-associated but not high-fat diet-induced hepatic steatosis." dans: Journal of lipid research, Vol. 53, Issue 3, pp. 358-67, (2012) (PubMed).

Liu, Hong, Wen, Han, Zuo, Liu, Cao: "Increased basal level of Akt-dependent insulin signaling may be responsible for the development of insulin resistance." dans: American journal of physiology. Endocrinology and metabolism, Vol. 297, Issue 4, pp. E898-906, (2010) (PubMed).

Holloway, Perry, Thrush, Heigenhauser, Dyck, Bonen, Spriet: "PGC-1alpha's relationship with skeletal muscle palmitate oxidation is not present with obesity despite maintained PGC-1alpha and PGC-1beta protein." dans: American journal of physiology. Endocrinology and metabolism, Vol. 294, Issue 6, pp. E1060-9, (2008) (PubMed).

Mathai, Bonen, Benton, Robinson, Graham: "Rapid exercise-induced changes in PGC-1alpha mRNA and protein in human skeletal muscle." dans: Journal of applied physiology (Bethesda, Md. : 1985), Vol. 105, Issue 4, pp. 1098-105, (2008) (PubMed).

Synonymes et noms alternatifs relatifs à PPARGC1B

PPARG coactivator 1 beta (PPARGC1B), peroxisome proliferative activated receptor, gamma, coactivator 1 beta (Ppargc1b), PPARG coactivator 1 beta (Ppargc1b), 4631412G21Rik, ERRL1, Perc, PERC, PGC-1(beta), PGC1B, PGC1beta, PPARGC1B

Protein level used designations for PPARGC1B

  • peroxisome proliferator-activated receptor gamma, coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1-beta-like
  • ERR ligand 1
  • PGC-1-beta
  • PGC-1beta
  • PGC-1beta/ERRL1
  • PPAR gamma coactivator-1beta protein
  • PPAR-gamma coactivator 1-beta
  • PPARGC-1-beta
  • peroxisome proliferator-activated receptor gamma coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1-beta
  • peroxisome proliferative activated receptor, gamma, coactivator 1 beta
  • peroxisome proliferator-activated receptor gamma coactivator 1beta-2a
  • PGC-1-related estrogen receptor alpha coactivator
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