PPARGC1B anticorps (AA 195-414)

N° du produit ABIN2683008

Cet anticorps Souris Monoclonal détecte spécifiquement PPARGC1B dans ELISA et FACS. Il présente une réactivité envers Humain.

Aperçu rapide pour PPARGC1B anticorps (AA 195-414) (ABIN2683008)

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PPARGC1B est non-conjugé

Application: ELISA, Flow Cytometry (FACS)

Clone: 6C3F6

Détail du produit anti-PPARGC1B anticorps

Épitope: AA 195-414

Fonction: PPARGC1B Antibody

Purification: Purified antibody

Immunogène: Purified recombinant fragment of human PPARGC1B (AA: 195-414) expressed in E. Coli.

Isotype: IgG1

Information d'application

Indications d'application:

ELISA: 1/10000

FCM: 1/200 - 1/400

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Détails sur PPARGC1B

Antigène: PPARGC1B (Peroxisome Proliferator-Activated Receptor Gamma, Coactivator 1 beta (PPARGC1B))

Autre désignation: PPARGC1B

Sujet: The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors, including estrogen receptor alpha, nuclear respiratory factor 1, and glucocorticoid receptor. The encoded protein may be involved in fat oxidation, non-oxidative glucose metabolism, and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Poids moléculaire: 113.2 kDa

ID gène: 133522

UniProt: Q86YN6

Pathways: AMPK Signaling, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha