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PPARA Produits

(Peroxisome Proliferator-Activated Receptor alpha (PPARA))

Catégories

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers\; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008].

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Catégories PPARA en vedette

PPARA Anticorps

High quality antibodies with extensive validation data.

PPARA Kits ELISA

Reliable ELISA kits for a wide range of species.

PPARA Protéines

Proteins for various applications incl. WB, ELISA, IF etc.

PPARA recommandé Anticorps

Produit
Reactivity
Application
Validations
N° du produit
Quantité
Fiche technique
Reactivity Chicken, Human, Mouse, Rat
Application WB, ELISA, FACS, IF (p), IF (cc), IHC (p), IHC (fro)
Validations
  • (1)
  • (5)
N° du produit ABIN701620
Quantité 100 μL
Fiche technique Fiche technique
Reactivity Human, Mouse
Application WB, FACS, IF, IHC (p)
Validations
  • (4)
  • (5)
N° du produit ABIN1944858
Quantité 400 μL
Fiche technique Fiche technique
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
N° du produit ABIN7432904
Quantité 100 μL
Fiche technique Fiche technique

PPARA recommandé Kits ELISA

Produit
Reactivity
Analytical Method
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
N° du produit ABIN6958498
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (2)
  • (1)
N° du produit ABIN6958500
Quantité 96 tests
Fiche technique Fiche technique
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
N° du produit ABIN6969234
Quantité 96 tests
Fiche technique Fiche technique

PPARA recommandé Protéines

Produit
Reactivity
Source
Validations
N° du produit
Quantité
Fiche technique
Reactivity Human
Source Wheat germ
Validations
  • (1)
N° du produit ABIN1315830
Quantité 10 μg
Fiche technique Fiche technique
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
N° du produit ABIN7124374
Quantité 50 μg
Fiche technique Fiche technique
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
N° du produit ABIN7505511
Quantité 100 μg
Fiche technique Fiche technique

Dernières publications sur nos produits PPARA

Li, Xiong, Yan, Gao, Cheng, Wu, Liu, Zhang, Li, Wang, Fan, Zhao, Zhang, Tao: "Branched chain amino acids exacerbate myocardial ischemia/reperfusion vulnerability via enhancing GCN2/ATF6/PPAR-α pathway-dependent fatty acid oxidation." dans: Theranostics, Vol. 10, Issue 12, pp. 5623-5640, (2021) (PubMed).

Kumar, Rani, Karns, Gandhi: "Augmenter of liver regeneration protein deficiency promotes hepatic steatosis by inducing oxidative stress and microRNA-540 expression." dans: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 3, pp. 3825-3840, (2019) (PubMed).

Krishnan, Baskaran, Thyagarajan: "Troglitazone activates TRPV1 and causes deacetylation of PPARγ in 3T3-L1 cells." dans: Biochimica et biophysica acta. Molecular basis of disease, Vol. 1865, Issue 2, pp. 445-453, (2019) (PubMed).

Ligresti, Caporarello, Meridew, Jones, Tan, Choi, Haak, Aravamudhan, Roden, Prakash, Lomberk, Urrutia, Tschumperlin: "CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis." dans: JCI insight, Vol. 5, (2019) (PubMed).

Renu, K B, Parthiban, S, George, P B, Suman, V G, Arunachalam: "Elevated lipolysis in adipose tissue by doxorubicin via PPARα activation associated with hepatic steatosis and insulin resistance." dans: European journal of pharmacology, Vol. 843, pp. 162-176, (2019) (PubMed).

Chiocchetti, Galiazzo, Tagliavia, Stanzani, Giancola, Menchetti, Militerno, Bernardini, Forni, Mandrioli: "Cellular Distribution of Canonical and Putative Cannabinoid Receptors in Canine Cervical Dorsal Root Ganglia." dans: Frontiers in veterinary science, Vol. 6, pp. 313, (2019) (PubMed).

Szalardy, Zadori, Bencsik, Vecsei, Klivenyi: "Unlike PPARgamma, neither other PPARs nor PGC-1alpha is elevated in the cerebrospinal fluid of patients with multiple sclerosis." dans: Neuroscience letters, Vol. 651, pp. 128-133, (2018) (PubMed).

Li, He, Xiao, Liu, Wang, Zhang: "Acetic Acid Influences BRL-3A Cell Lipid Metabolism via the AMPK Signalling Pathway." dans: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 45, Issue 5, pp. 2021-2030, (2018) (PubMed).

Yang, Fu, Hu, Luo, Hu, Wang: "PIK3R3 regulates PPARα expression to stimulate fatty acid β-oxidation and decrease hepatosteatosis." dans: Experimental & molecular medicine, Vol. 50, Issue 1, pp. e431, (2018) (PubMed).

Galiazzo, Giancola, Stanzani, Fracassi, Bernardini, Forni, Pietra, Chiocchetti: "Localization of cannabinoid receptors CB1, CB2, GPR55, and PPARα in the canine gastrointestinal tract." dans: Histochemistry and cell biology, Vol. 150, Issue 2, pp. 187-205, (2018) (PubMed).

Synonymes et noms alternatifs relatifs à PPARA

peroxisome proliferator activated receptor alpha (PPARA), peroxisome proliferator-activated receptor alpha (LOC100136415), peroxisome proliferator activated receptor alpha L homeolog (ppara.L), peroxisome proliferator activated receptor alpha (Ppara), peroxisome proliferator activated receptor alpha (ppara), 4933429D07Rik, AW742785, hPPAR, LOC100136415, NR1C1, nr1c1, Nr1c1, PPAR, Ppar, PPAR-alpha, PPARalpha, PPARALPHA, xppara, xPPARalpha

Protein level used designations for PPARA

  • PPAR-alpha
  • nuclear receptor subfamily 1 group C member 1
  • peroxisome proliferative activated receptor, alpha
  • peroxisome proliferator-activated nuclear receptor alpha variant 3
  • PPAR alpha
  • peroxisome proliferator activated receptor alpha
  • peroxisome proliferator-activated receptor alpha
  • ppar alpha
  • xPPAR alpha
  • peroxisome proliferator-activated receptor-alpha
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