NGFB Protéine

N° du produit ABIN1880418

Cette protéine Native NGFB est exprimée dans Souris.

Aperçu rapide pour NGFB Protéine (ABIN1880418)

Antigène: NGFB (Nerve Growth Factor beta (NGFB))

Type de proteíne: Native

Activité biologique: Active

Origine: Souris

Source: Souris

Pureté: > 95 % by SDS-PAGE

Détail du produit

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with sterile 18 mΩ/cm^3 H2O.

Buffer: 10 mM Phosphate buffer and 200 mM NaCl (pH 7.0)

Agent conservateur: Without preservative

Stock: 4 °C

Détail du antigène

Antigène: NGFB (Nerve Growth Factor beta (NGFB))

Autre désignation: NGF beta

Sujet: Nerve growth factor (NGF) is a polypeptide involved in the regulation of growth and differentiation of sympathetic and certain sensory neurons. NGF consists of 3 types of subunits, alpha, beta and gamma, which specifically interact to form a 7S, approximately 130,000-molecular weight complex. It is mainly expressed in Sertoli and interstitial cells. The proforms of NGF are secreted and cleaved extracellularly by the serine protease plasmin and by selective matrix metalloproteinases. NGF is important for the growth, maintenance, and survival of certain target neurons (nerve cells). It also functions as a signaling molecule.

Poids moléculaire: 26.5 kDa

Pathways: Signalisation NF-kappaB, Signalisation RTK, Regulation of Cell Size