Oncostatin M Protein (OSM) (AA 24-206)

N° du produit ABIN2018306

Cette protéine Recombinant Oncostatin M est exprimée dans HEK-293T Cells.

Aperçu rapide pour Oncostatin M Protein (OSM) (AA 24-206) (ABIN2018306)

Antigène: Oncostatin M (OSM)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: HEK-293T Cells

Pureté: > 95 % as analyzed by SDS-PAGE and HPLC.

Détail du produit

Attributs du protein: AA 24-206

Attributs du produit: ED50 < 0.4 ng/mL, measured in a cell proliferation assay using NIH-3T3 cells.

niveau d'endotoxine: < 0.2 EU/μg, determined by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Stock: -80 °C

Stockage commentaire: Lyophilized recombinant Murine Oncostatin-M remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Murine Oncostatin-M should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Date de péremption: 6 months

Détail du antigène

Antigène: Oncostatin M (OSM)

Autre désignation: Oncostatin-M (OSM)

Sujet: Oncostatin-M, also known as OSM, is a growth regulator belonging to the interleukin-6 group of cytokines. It is expressed mainly by monocytes, activated T cells and Kaposi's sarcoma cells. OSM signals through two types of receptors, one is composed of gp130 and LIFR, and the other is composed of gp130 and OSMR. OSM regulates IL-6, G-CSF and GM-CSF production, and thus is involved in hematopoiesis, neurogenesis and osteogenesis. OSM displays both stimulatory and inhibitory effects, so its categorization as pro-inflammatory or anti-inflammatory cytokine is still controversial.
Synonyms: OSM

Poids moléculaire: 10-40 kDa, observed by reducing SDS-PAGE.

UniProt: P53347

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion