Midkine Protéine
Aperçu rapide pour Midkine Protéine (ABIN2468825)
Antigène
Voir toutes Midkine (MDK) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Séquence
- MVAKKKEKVK KGSECSEWTW GPCTPSSKDC GMGFREGTCG AQTQRVHCKV PCNWKKEFGA DCKYKFESWG ACDGSTGTKA RQGTLKKARY NAQCQETIRV TKPCTSKTKS KTKAKKGKGK D
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Attributs du produit
- Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 10-100 ng/mL.
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niveau d'endotoxine
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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Midkine (Neurite Growth-Promoting Factor 2) (MDK) (Active) protein
MDK Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His-Avi Tag)MDK Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-140) protein (His tag)MDK Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-140) protein (His-IF2DI Tag)MDK Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 1-143) protein (GST tag)MDK Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (His tag)MDK Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 21-143) protein (Fc Tag)MDK Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
Midkine (Neurite Growth-Promoting Factor 2) (MDK) (AA 23-143) protein (Fc Tag)MDK Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Conseil sur la manipulation
- As with any protein, exposing Midkine recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
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Stock
- -20 °C
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Stockage commentaire
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted Midkine stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
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Date de péremption
- 24 months
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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Autre désignation
- Midkine
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Sujet
- Midkine and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant murine Midkine is a 13.4 kDa protein containing 121 amino acid residues including five intra-molecular disulfide bonds.
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ID gène
- 17242
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NCBI Accession
- NP_001012335
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OMIM
- 59894790
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UniProt
- P12025
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Pathways
- Signalisation RTK, M Phase, Skeletal Muscle Fiber Development
Antigène
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