FGF5 Protein (Transcript Variant 2)
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- Antigène Voir toutes FGF5 Protéines
- FGF5 (Fibroblast Growth Factor 5 (FGF5))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- Transcript Variant 2
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)
- Specificité
- Optimal preservation of protein structure, post-translational modifications and functions.
- Attributs du produit
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- Recombinant human FGF5 (transcript variant 2) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Pureté
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- niveau d'endotoxine
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF-receptors is less than or equal to 0.5 ng/ml, corresponding to a specific activity of > 2 x 10^6 units/mg.
- Top Product
- Discover our top product FGF5 Protéine
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- Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Conseil sur la manipulation
- Resuspend the protein in the desired concentration in proper buffer
- Stock
- -80 °C
- Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Antigène
- FGF5 (Fibroblast Growth Factor 5 (FGF5))
- Autre désignation
- Fgf5 (FGF5 Produits)
- Synonymes
- FGF5 Protein, HBGF-5 Protein, Smag-82 Protein, Fgf-5 Protein, angora Protein, go Protein, FGF-5 Protein, fibroblast growth factor 5 Protein, FGF5 Protein, fgf5 Protein, Fgf5 Protein
- Sujet
- The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene was identified as an oncogene, which confers transforming potential when transfected into mammalian cells. Targeted disruption of the homolog of this gene in mouse resulted in the phenotype of abnormally long hair, which suggested a function as an inhibitor of hair elongation. Alternatively spliced transcript variants encoding different isoforms have been identified.
- Poids moléculaire
- 27.6 kDa
- NCBI Accession
- NP_004455
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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