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HRG Protein (Myc-DYKDDDDK Tag)

Protéine Recombinant HRG exprimée dans HEK-293 Cells.
N° du produit ABIN2722778

Aperçu rapide pour HRG Protein (Myc-DYKDDDDK Tag) (ABIN2722778)

Antigène

Voir toutes HRG Protéines
HRG (Histidine-Rich Glycoprotein (HRG))

Type de proteíne

Recombinant

Origine

  • 8
  • 3
  • 3
  • 1
Humain

Source

  • 6
  • 5
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Pureté

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Purification/Conjugué

    Cette HRG protéine est marqué à la Myc-DYKDDDDK Tag.

    Attributs du produit

    • Recombinant human Histidine-rich glycoprotein / HRG protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Indications d'application

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Commentaires

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Stock

    -80 °C

    Stockage commentaire

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène

    HRG (Histidine-Rich Glycoprotein (HRG))

    Autre désignation

    Histidine-Rich Glycoprotein,hrg

    Sujet

    This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein&aposs effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.

    Poids moléculaire

    57.6 kDa

    NCBI Accession

    NP_000403
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