Tel:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@anticorps-enligne.fr

MGMT Protein (Myc-DYKDDDDK Tag)

MGMT Origine: Humain Hôte: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
N° du produit ABIN2727841
  • Antigène Voir toutes MGMT Protéines
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Type de proteíne
    Recombinant
    Origine
    • 7
    • 2
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette MGMT protéine est marqué à la Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Attributs du produit
    • Recombinant human O-6-methylguanine-DNA methyltransferase (MGMT) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Pureté
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MGMT Protéine
  • Indications d'application
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Commentaires

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Stock
    -80 °C
    Stockage commentaire
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Antigène
    MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))
    Autre désignation
    O-6-Methylguanine-Dna Methyltransferase (Mgmt) (MGMT Produits)
    Synonymes
    AGT Protein, AI267024 Protein, Agat Protein, O-6-methylguanine-DNA methyltransferase Protein, MGMT Protein, Mgmt Protein
    Sujet
    Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. [UniProtKB/Swiss-Prot Function]
    Poids moléculaire
    24.9 kDa
    NCBI Accession
    NP_002403
    Pathways
    Réparation de l'ADN, Positive Regulation of Response to DNA Damage Stimulus
Vous êtes ici:
Support technique