RAC1 Protein (Myc-DYKDDDDK Tag)
Aperçu rapide pour RAC1 Protein (Myc-DYKDDDDK Tag) (ABIN2730391)
Antigène
Type de proteíne
Origine
Source
Application
Pureté
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Purification/Conjugué
- Cette RAC1 protéine est marqué à la Myc-DYKDDDDK Tag.
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Attributs du produit
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- Recombinant human RAC1 (transcript variant Rac1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Indications d'application
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Commentaires
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The tag is located at the C-terminal.
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Restrictions
- For Research Use only
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Concentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Stock
- -80 °C
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Stockage commentaire
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- RAC1
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Sujet
- Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]
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Poids moléculaire
- 21.3 kDa
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NCBI Accession
- NP_008839
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Pathways
- Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling
Antigène
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