RAC1 Protein (Myc-DYKDDDDK Tag)

N° du produit ABIN2730391

Détail du produit

Antigène: RAC1

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette RAC1 protéine est marqué à la Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Attributs du produit:

• Recombinant human RAC1 (transcript variant Rac1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: RAC1

Abstract: RAC1 Produits

Synonymes: Rac-1 Protein, TC-25 Protein, p21-Rac1 Protein, AL023026 Protein, D5Ertd559e Protein, RAC2 Protein, CRAC1A Protein, rac1 Protein, wu:fd16e02 Protein, zgc:55823 Protein, zgc:55917 Protein, zgc:86934 Protein, 2248 Protein, CG2248 Protein, D-Rac Protein, D-Rac 1 Protein, D-Rac1 Protein, DRac Protein, DRac1 Protein, DRacA Protein, Dm Rac1 Protein, DmRAC Protein, DmRAC1 Protein, Dmel\CG2248 Protein, Dmrac1 Protein, Drac Protein, Drac1 Protein, Drac1a Protein, DracA Protein, GTPase Rac1 Protein, P40792 Protein, RAC1 Protein, Rac Protein, Rac GTPase Protein, Rac3 Protein, RacA Protein, dRac Protein, dRac1 Protein, drac1 Protein, rac Protein, Xrac Protein, mig5 Protein, p21-rac1 Protein, tc-25 Protein, Rac family small GTPase 1 Protein, RAS-related C3 botulinum substrate 1 Protein, ras-related C3 botulinum toxin substrate 1 Protein, ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Protein, Rac family small GTPase 1a Protein, CG2248 gene product from transcript CG2248-RB Protein, Rac family small GTPase 1 L homeolog Protein, ras homolog family member G Protein, RAC1 Protein, Rac1 Protein, rac1a Protein, rac1.L Protein, RHOG Protein

Sujet: Isoform B has an accelerated GEF-independent GDP/GTP exchange and an impaired GTP hydrolysis, which is restored partially by GTPase-activating proteins. It is able to bind to the GTPase-binding domain of PAK but not full-length PAK in a GTP-dependent manner, suggesting that the insertion does not completely abolish effector interaction. [UniProtKB/Swiss-Prot Function]

Poids moléculaire: 21.3 kDa

NCBI Accession: NP_008839

Pathways: Signalisation WNT, Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Thromboxane A2 Receptor Signaling, VEGF Signaling