CD86 Protein (CD86) (DYKDDDDK-His Tag)

N° du produit ABIN5505589

Cette protéine Recombinant CD86 est exprimée dans HEK-293 Cells.

Aperçu rapide pour CD86 Protein (CD86) (DYKDDDDK-His Tag) (ABIN5505589)

Antigène: CD86

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Antibody Production (AbP), Standard (STD)

Pureté: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Détail du produit

Purification/Conjugué: Cette CD86 protéine est marqué à la DYKDDDDK-His Tag.

Attributs du produit:

• Recombinant human Purified recombinant protein of human CD86 Molecule (CD86), transcript variant 1, with C-terminal DDK/His tag, expressed in human cells, 20 μg (C-term DDK/His tag, transcript variant 1) protein expressed in Human HEK293 cells.
• Produced with end-sequenced ORF clone

Purification: Purified

Information d'application

Indications d'application: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Commentaires:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Stockage

Concentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol.

Stock: -80 °C

Stockage commentaire: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Détail du antigène

Antigène: CD86

Autre désignation: CD86 molecule

Sujet: This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.[provided by RefSeq, May 2011].

Poids moléculaire: 27 kDa

NCBI Accession: NP_787058

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation