Betacellulin Protein (BTC) (partial) (Fc Tag)
Aperçu rapide pour Betacellulin Protein (BTC) (partial) (Fc Tag) (ABIN5608199)
Antigène
Voir toutes Betacellulin (BTC) ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- partial
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Purification/Conjugué
- Cette Betacellulin protéine est marqué à la Fc Tag.
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Séquence
- Asp 32 - Tyr 111
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niveau d'endotoxine
- Endotoxin level is less than 1.0 EU per ug by the LAL method.
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Betacellulin (BTC) (AA 32-111) protein (His-IF2DI Tag)
BTC Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Betacellulin (BTC) (AA 32-111) protein (His-IF2DI Tag)BTC Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Betacellulin (BTC) (AA 1-178) protein (GST tag)BTC Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Betacellulin (BTC) (AA 32-111) protein (Fc Tag)BTC Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
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Indications d'application
- This recombinant protein can be used for WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, pH 7.5
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Conseil sur la manipulation
- Avoid repeated freeze-thaw cycles.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
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- Betacellulin (BTC)
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Autre désignation
- Betacellulin
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Sujet
- Probetacellulin can be cleaved into the Betacellulin (BTC) that is a single-pass type I membrane protein containing 1 EGF-like domain. Predominantly expressed in pancreas and small intestine,Betacellulin (BTC) is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. As a potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells, Betacellulin (BTC) is also the growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Betacellulin (BTC) was originally identified as a growth-promoting factor in mouse pancreatic beta-cell carcinoma cell line and has since been identified in humans. The amino acid sequence of mature mBTC is 82.5 % , identical with that of human BTC (hBTC), and both exhibit significant overall similarity with other members of the EGF family.
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Poids moléculaire
- 36.5 kDa
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ID gène
- 685
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UniProt
- P35070
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Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
Antigène
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