LAMP2 Protein (AA 26-379) (His tag)

N° du produit ABIN5854611

Détail du produit

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Type de proteíne: Recombinant

Attributs du protein: AA 26-379

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette LAMP2 protéine est marqué à la His tag.

Application: SDS-PAGE (SDS)

Séquence: LIVNLTDSKG TCLYAEWEMN FTITYETTNQ TNKTITIAVP DKATHDGSSC GDDRNSAKIM IQFGFAVSWA VNFTKEASHY SIHDIVLSYN TSDSTVFPGA VAKGVHTVKN PENFKVPLDV IFKCNSVLTY NLTPVVQKYW GIHLQAFVQN GTVSKNEQVC EEDQTPTTVA PIIHTTAPST TTTLTPTSTP TPTPTPTPTV GNYSIRNGNT TCLLATMGLQ LNITEEKVPF IFNINPATTN FTGSCQPQSA QLRLNNSQIK YLDFIFAVKN EKRFYLKEVN VYMYLANGSA FNISNKNLSF WDAPLGSSYM CNKEQVLSVS RAFQINTFNL KVQPFNVTKG QYSTAQDCSA DEDNLEHHHH HH

Pureté: > 95 % by SDS - PAGE

niveau d'endotoxine: < 1.0 EU per 1 microgram of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In Phosphate Buffered Saline (  pH 7.4) containing 10 % glycerol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Autre désignation: Lamp2 (LAMP2 Produits)

Synonymes: CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein

Sujet: Lamp2, also known as lysosome-associated membrane glycoprotein 2, is a major component of lysosomal membranes. It is clinically characterized by cardiomyopathy, myopathy, and variable mental retardation. Up-regulated Lamp2 at the plasma membrane serves as an indicator of cell activation of CD8+ T cells, mast cells, monocytes, and platelets. Recombinant mouse Lamp2, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 40.2kDa (362aa) 50-70KDa (SDS-PAGE under reducing conditions)

NCBI Accession: NP_001017959

UniProt: P17047

Pathways: Autophagy