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LAMP2 Protein (AA 29-375) (His tag)
LAMP2
Origine: Humain
Hôte: Baculovirus infected Insect Cells
Recombinant
> 90 % by SDS - PAGE
SDS
N° du produit ABIN5855013
Détail du produit
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Antigène
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LAMP2
(Lysosomal-Associated Membrane Protein 2 (LAMP2))
Type de proteíne
Recombinant
Attributs du protein
AA 29-375
Origine
Toutes les origines à travers LAMP2 Protéines
Humain
Source
Toutes les sources à travers LAMP2 Protéines
Baculovirus infected Insect Cells
Purification/Conjugué
Cette LAMP2 protéine est marqué à la His tag.
Application
SDS-PAGE (SDS)
Séquence
ADPLELNLTD SENATCLYAK WQMNFTVRYE TTNKTYKTVT ISDHGTVTYN GSICGDDQNG PKIAVQFGPG FSWIANFTKA ASTYSIDSVS FSYNTGDNTT FPDAEDKGIL TVDELLAIRI PLNDLFRCNS LSTLEKNDVV QHYWDVLVQA FVQNGTVSTN EFLCDKDKTS TVAPTIHTTV PSPTTTPTPK EKPEAGTYSV NNGNDTCLLA TMGLQLNITQ DKVASVININ PNTTHSTGSC RSHTALLRLN SSTIKYLDFV FAVKNENRFY LKEVNISMYL VNGSVFSIAN NNLSYWDAPL GSSYMCNKEQ TVSVSGAFQI NTFDLRVQPF NVTQGKYSTA QDCSADDDNF HHHHHH
Pureté
> 90 % by SDS - PAGE
niveau d'endotoxine
< 1.0 EU per 1ug of protein (determined by LAL method)
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Information d'application
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Indications d'application
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Stockage
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Format
Liquid
Concentration
0.5 mg/mL
Buffer
Liquid. In Phosphate Buffered Saline ( pH 7.4) containing 10 % glycerol.
Stock
4 °C,-20 °C,-80 °C
Stockage commentaire
Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Détail du antigène
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Antigène
LAMP2
(Lysosomal-Associated Membrane Protein 2 (LAMP2))
Autre désignation
LAMP2 (LAMP2 Produits )
Synonymes
CD107b Protein, LAMP-2 Protein, LAMPB Protein, LGP110 Protein, Lamp-2 Protein, Lamp-2a Protein, Lamp-2b Protein, Lamp-2c Protein, Mac3 Protein, cd107b Protein, lamp-2 Protein, lampb Protein, LAMP2 Protein, lamp2 Protein, DKFZp459J126 Protein, LGP-B Protein, sb:cb587 Protein, wu:fb14a06 Protein, zgc:103532 Protein, lysosomal associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 Protein, lysosomal-associated membrane protein 2 S homeolog Protein, lysosomal membrane glycoprotein 2 Protein, LAMP2 Protein, Lamp2 Protein, lamp2.S Protein, lamp2 Protein
Sujet
LAMP2, also known as lysosome-associated membrane glycoprotein 2 isoform A, is a major component of lysosomal membranes. It provides selectins with carbohydrate ligands. This protein mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. Deficiency of LAMP2 is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. Recombinant human LAMP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Poids moléculaire
39.4kDa (356aa) 57-70KDa (SDS-PAGE under reducing conditions.)
NCBI Accession
NP_002285
UniProt
P13473
Pathways
Autophagy
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