LAMP2 Protein (AA 29-375) (His tag)

N° du produit ABIN5855013

Cette protéine Recombinant LAMP2 est exprimée dans Baculovirus infected Insect Cells.

Aperçu rapide pour LAMP2 Protein (AA 29-375) (His tag) (ABIN5855013)

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Type de proteíne: Recombinant

Origine: Humain

Source: Baculovirus infected Insect Cells

Application: SDS-PAGE (SDS)

Pureté: > 90 %

Détail du produit

Attributs du protein: AA 29-375

Purification/Conjugué: Cette LAMP2 protéine est marqué à la His tag.

Séquence: ADPLELNLTD SENATCLYAK WQMNFTVRYE TTNKTYKTVT ISDHGTVTYN GSICGDDQNG PKIAVQFGPG FSWIANFTKA ASTYSIDSVS FSYNTGDNTT FPDAEDKGIL TVDELLAIRI PLNDLFRCNS LSTLEKNDVV QHYWDVLVQA FVQNGTVSTN EFLCDKDKTS TVAPTIHTTV PSPTTTPTPK EKPEAGTYSV NNGNDTCLLA TMGLQLNITQ DKVASVININ PNTTHSTGSC RSHTALLRLN SSTIKYLDFV FAVKNENRFY LKEVNISMYL VNGSVFSIAN NNLSYWDAPL GSSYMCNKEQ TVSVSGAFQI NTFDLRVQPF NVTQGKYSTA QDCSADDDNF HHHHHH

Purification: > 90% by SDS-PAGE

niveau d'endotoxine: < 1 EU per 1ug of protein (determined by LAL method)

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Détail du antigène

Antigène: LAMP2 (Lysosomal-Associated Membrane Protein 2 (LAMP2))

Autre désignation: CD107b/LAMP2

Sujet: LAMP2, also known as lysosome-associated membrane glycoprotein 2 isoform A, is a major component of lysosomal membranes. It provides selectins with carbohydrate ligands. This protein mediates the lysosomal uptake of the chaperone HSC73 in complex with cargo proteins and is required for the lysosomal destruction of autophagic vacuoles. Deficiency of LAMP2 is a rare X-linked lysosomal disease characterized by cardiomyopathy, vacuolar myopathy, and mental retardation. Recombinant human LAMP2 protein, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Poids moléculaire: 39.4 kDa (356aa)

NCBI Accession: NP_002285

Pathways: Autophagy