Granulin Protein (GRN) (DYKDDDDK Tag)

N° du produit ABIN622274

Cette protéine Recombinant Granulin est exprimée dans .

Aperçu rapide pour Granulin Protein (GRN) (DYKDDDDK Tag) (ABIN622274)

Antigène: Granulin (GRN)

Type de proteíne: Recombinant

Origine: Humain

Hôte: Veuillez nous consulter SVP

Pureté: > 90.0 % as determined by: a) Analysis by RP-HPLC. b) Analysis by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Granulin protéine est marqué à la DYKDDDDK Tag.

Attributs du produit: Recombinant Human Progranulin

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: The protein solution contains 1x PBS.

Stock: -20 °C

Détail du antigène

Antigène: Granulin (GRN)

Autre désignation: Progranulin

Classe de substances: Viral Protein

Sujet: Progranulin Human Recombinant fused to DYKDDDDK at C-terminus produced in HEK is a single, glycosylated, polypeptide chain containing 593 AA and having a molecular mass of 88 kDa. The Progranulin is purified by standard chromatographic techniques. Introduction: A 88 kDa progranulin, also called proepithelin and PC cell-derived growth factor, is a single precursor protein of granulins which are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Granulins are a variety of active, 6 kDa peptides and named granulin A (epithelin 1), granulin B (epithelin 2), granulin C, etc. Both the peptides and intact progranulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. Synonyms: GRN, PGRN, granulin, Acrogranin, propithelin, PC cell derived growth Factor, GEP, GP88, PEPI, PCDGF.