Leptin Protein (LEP)

N° du produit ABIN622843

Cette protéine Recombinant Leptin est produite dans not_set. Il y a 1 publication disponible.

Aperçu rapide pour Leptin Protein (LEP) (ABIN622843)

Antigène: Leptin (LEP)

Type de proteíne: Recombinant

Origine: Porc

Hôte: Veuillez nous consulter SVP

Pureté: > 95.0 % as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Détail du produit

Séquence: The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Pro-Ile-Arg.

Attributs du produit: Recombinant Porcine Leptin

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: Protein quantitation was carried out by two independent methods: 1. UV spectroscopy at 280 nm using the absorbency value of 0.53 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program

Buffer: The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3.It is recommended to reconstitute the lyophilized Leptin in sterile 18M -cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Stock: -20 °C

Référence

McNulty, Miller, OConnor, Guilak: "The effects of adipokines on cartilage and meniscus catabolism." dans: Connective tissue research, Vol. 52, Issue 6, pp. 523-33, (2012) (PubMed).

Détail du antigène

Antigène: Leptin (LEP)

Autre désignation: Leptin

Sujet: Leptin Porcine Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 146 amino acids and having a molecular mass of 16 kDa. The Leptin is purified by proprietary chromatographic techniques. Introduction: A 16-kDa peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Leptin provides the key afferent signal from fat cells in the feedback system that controls body fat stores. Synonyms: OB Protein, Obesity Protein, OBS, Obesity factor.

Pathways: Signalistation JAK/STAT, AMPK Signaling, Hormone Transport, Peptide Hormone Metabolism, Hormone Activity, Negative Regulation of Hormone Secretion, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Monocarboxylic Acid Catabolic Process