IL11RA Protein (AA 24-371) (His tag)
Aperçu rapide pour IL11RA Protein (AA 24-371) (His tag) (ABIN7281150)
Antigène
Voir toutes IL11RA ProtéinesType de proteíne
Origine
Source
Application
Pureté
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Attributs du protein
- AA 24-371
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Purification/Conjugué
- Cette IL11RA protéine est marqué à la His tag.
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Séquence
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TPCPQAWGPP GVQYGQPGRP VMLCCPGVNA GTPVSWFRDG DSRLLQGPDS GLGHRLVLAQ VDSRDEGTYV CRTLDGVFGG MVTLKLGSPP ARPEVSCQAV DYENFSCTWS PGRVSGLPTR YLTSYRKKTL PGAESQRESP STGPWPCPQD PLEASRCVVH GAEFWSEYRI NVTEVNPLGA STCLLDVRLQ RILRPDPPQG LRVESVPGYP RRLHASWTYP ASWRRQPHFL LKFRLQYRPA QHPAWSTVEP IGLEELITDA VAGLPHAVRV SARDFLDAGT WSAWSPEAWG TPSTGPLRDE VPDGSRGHEQ KLEAAAQEDS PAPPSPSLQP DPRPLDHRDP LEQVAVLA
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Purification
- > 85% by SDS-PAGE
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niveau d'endotoxine
- < 1 EU per 1ug of protein (determined by LAL method)
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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Bioactivity Validated
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.25 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) containing 10 % glycerol
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Stock
- 4 °C,-20 °C,-80 °C
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Stockage commentaire
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
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Autre désignation
- IL-11R alpha/IL11RA
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Sujet
- Il11ra1, also known as interleukin-11 receptor subunit alpha, is a subunit of the interleukin 11 receptor which is a member of the hematopoietic cytokine receptor family. It can utilize IL6ST for initiating signal transmission. It is expressed in a number of cell lines, including the myelogenous leukemia cell line K562, the megakaryocytic leukemia cell line Mo7E, the erythroleukemia cell line TF1, and the osteosarcoma cell lines, MG-63 and Saos-2. It is also expressed in normal and malignant prostate epithelial cell lines. Recombinant rat Il11ra1, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
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Poids moléculaire
- 39.2 kDa (356aa)
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NCBI Accession
- NP_620816
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Pathways
- Signalistation JAK/STAT, Growth Factor Binding
Antigène
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