IL11RA Protein (AA 24-370) (Fc Tag)
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- Antigène Voir toutes IL11RA Protéines
- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
- Attributs du protein
- AA 24-370
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette IL11RA protéine est marqué à la Fc Tag.
- Fonction
- Human IL-11 R alpha Protein, Fc Tag (MALS verified)
- Pureté
- >90 % as determined by SDS-PAGE.
- niveau d'endotoxine
- Less than 1.0 EU per μg by the LAL method.
- Top Product
- Discover our top product IL11RA Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
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- Antigène
- IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
- Autre désignation
- IL-11 R alpha (IL11RA Produits)
- Synonymes
- CRSDA Protein, fi26e06 Protein, il-11ra Protein, wu:fi26e06 Protein, AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor subunit alpha Protein, interleukin 11 receptor, alpha Protein, interleukin 11 receptor subunit alpha 1 Protein, interleukin 11 receptor, alpha chain 1 Protein, IL11RA Protein, il11ra Protein, Il11ra1 Protein, Il11ra Protein
- Sujet
- Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
- Poids moléculaire
- 64.3 kDa
- NCBI Accession
- NP_001136256
- Pathways
- Signalistation JAK/STAT, Growth Factor Binding
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