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IL11RA Protein (AA 24-370) (Fc Tag)

IL11RA Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE. Active
N° du produit ABIN6992343
  • Antigène Voir toutes IL11RA Protéines
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Attributs du protein
    AA 24-370
    Origine
    • 10
    • 5
    • 1
    Humain
    Source
    • 6
    • 5
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IL11RA protéine est marqué à la Fc Tag.
    Fonction
    Human IL-11 R alpha Protein, Fc Tag (MALS verified)
    Pureté
    >90 % as determined by SDS-PAGE.
    niveau d'endotoxine
    Less than 1.0 EU per μg by the LAL method.
    Top Product
    Discover our top product IL11RA Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
  • Antigène
    IL11RA (Interleukin 11 Receptor, alpha (IL11RA))
    Autre désignation
    IL-11 R alpha (IL11RA Produits)
    Synonymes
    CRSDA Protein, fi26e06 Protein, il-11ra Protein, wu:fi26e06 Protein, AI314697 Protein, GP130 Protein, Il-11ra Protein, Il11ra Protein, Il11ra2 Protein, NR1 Protein, interleukin 11 receptor subunit alpha Protein, interleukin 11 receptor, alpha Protein, interleukin 11 receptor subunit alpha 1 Protein, interleukin 11 receptor, alpha chain 1 Protein, IL11RA Protein, il11ra Protein, Il11ra1 Protein, Il11ra Protein
    Sujet
    Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.Soluble form of IL11 receptor (sIL11RA) that acts as an agonist of IL11 activity. The IL11:sIL11RA complex binds to IL6ST/gp130 on cell surfaces and induces signaling also on cells that do not express membrane-bound IL11RA in a process called IL11 trans-signaling.
    Poids moléculaire
    64.3 kDa
    NCBI Accession
    NP_001136256
    Pathways
    Signalistation JAK/STAT, Growth Factor Binding
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