DDIT4 Protein (AA 1-232) (His tag)
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- Antigène Voir toutes DDIT4 Protéines
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-232
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette DDIT4 protéine est marqué à la His tag.
- Application
- SDS-PAGE (SDS)
- Attributs du produit
- DDIT4, 1-232aa, Human, His tag, E.coli
- Pureté
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product DDIT4 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/ml (determined by Bradford assay)
- Buffer
- Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
- Stock
- 4 °C
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- Antigène
- DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
- Autre désignation
- DDIT4 (DDIT4 Produits)
- Synonymes
- redd1 Protein, Dig2 Protein, REDD-1 Protein, REDD1 Protein, 5830413E08Rik Protein, AA415483 Protein, Rtp801 Protein, dig2 Protein, rtp801 Protein, sb:cb821 Protein, zgc:64114 Protein, DNA damage inducible transcript 4 Protein, DNA-damage-inducible transcript 4 Protein, DNA damage inducible transcript 4 S homeolog Protein, ddit4 Protein, DDIT4 Protein, Ddit4 Protein, ddit4.S Protein
- Sujet
- DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801. NCBI no.: NP_061931
- Poids moléculaire
- 27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
- Pathways
- Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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