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DDIT4 Protein (AA 1-232) (His tag)

DDIT4 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
N° du produit ABIN667871
  • Antigène Voir toutes DDIT4 Protéines
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-232
    Origine
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Source
    • 4
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette DDIT4 protéine est marqué à la His tag.
    Application
    SDS-PAGE (SDS)
    Attributs du produit
    DDIT4, 1-232aa, Human, His tag, E.coli
    Pureté
    > 90 % by SDS - PAGE
    Top Product
    Discover our top product DDIT4 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/ml (determined by Bradford assay)
    Buffer
    Liquid. In 20 mM Tris-HCl buffer (pH8.0) containing 0.2M NaCl, 5mM DTT, 1mM EDTA, 30% glycerol
    Stock
    4 °C
  • Antigène
    DDIT4 (DNA-Damage-Inducible Transcript 4 (DDIT4))
    Autre désignation
    DDIT4 (DDIT4 Produits)
    Synonymes
    redd1 Protein, Dig2 Protein, REDD-1 Protein, REDD1 Protein, 5830413E08Rik Protein, AA415483 Protein, Rtp801 Protein, dig2 Protein, rtp801 Protein, sb:cb821 Protein, zgc:64114 Protein, DNA damage inducible transcript 4 Protein, DNA-damage-inducible transcript 4 Protein, DNA damage inducible transcript 4 S homeolog Protein, ddit4 Protein, DDIT4 Protein, Ddit4 Protein, ddit4.S Protein
    Sujet
    DDIT4, also known as Dig2 or REDD1, is thought to have function in the regulation of reactive oxygen species. In response to stress due to DNA damage and glucocorticoid treatment, DDIT4 is upregulated at the transcriptional level. DDIT4 negatively regulates the mammalian target of Rapamycin, a serine/threonine kinase often referred to as mTOR. It is crucial in the coupling of extra- and intracellular cues to mTOR regulation. Recombinant human DDIT4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. Synonyms: DNA damage-inducible transcript 4 protein, Dig2, FLJ20500, REDD1, RP11-442H21.1, RTP801. NCBI no.: NP_061931
    Poids moléculaire
    27.5 kDa (252aa) confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher)
    Pathways
    Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process
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