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GDNF Protéine

Protéine Recombinant GDNF exprimée dans Escherichia coli (E. coli).
Rockland
N° du produit ABIN6700947
N° du produit (Fournisseur): 012-001-v10-0010

Aperçu rapide pour GDNF Protéine (ABIN6700947)

Antigène

Voir toutes GDNF Protéines
GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

Type de proteíne

Recombinant

Origine

  • 18
  • 8
  • 4
  • 1
Rat

Source

  • 22
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Application

SDS-PAGE (SDS)

Pureté

98,00%
  • N° du produit (Fournisseur)

    012-001-v10-0010

    Fournisseur

    Rockland

    Fonction

    Rat Glial Derived Neurotrophic Factor Recombinant Protein

    Purification

    Glial Derived Neurotrophic Factor purity was determined to be greater than 98% as determined by analysis by reducing and non-reducing SDS-pAGE.

    niveau d'endotoxine

    Measured by LAL is typically ≤ 1 EU/μg protein.

    Biological Activity Comment

    The activity is determined by the dose-dependent proliferation of C6 cells and is typically less than 0.1 μg/mL.
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  • Indications d'application

    Application Note: Glial Derived Neurotrophic Factor Recombinant Protein has been tested by biological activity and is suitable as a control for polyclonal or monoclonal anti-Glial Derived Neurotrophic Factor in immunological assays.

    Other: User Optimized

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Reconstitution_Buffer: Restore with deionized water (or equivalent)

    Reconstitution_Volume: 10 μL (10-100 μL)

    Buffer

    Buffer: 0.01 M Sodium Phosphate, pH 7.5

    Stabilizer: None

    Agent conservateur

    Without preservative

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store vial at 4° C prior to restoration. Dilute only prior to immediate use. Maintain sterility. This product DOES NOT contain preservative. DO NOT VORTEX. We recommend adding a carrier protein such as HSA or BSA to 0.1% (i.e. 1.0 mg/mL). For best results aliquot contents and freeze at -20° C or colder. Avoid cycles of freezing and thawing. Centrifuge vial before each opening to dislodge contents from the cap and to clarify if contents are not clear after standing at room temperature.

    Date de péremption

    6 months
  • Antigène

    GDNF (Glial Cell Line Derived Neurotrophic Factor (GDNF))

    Autre désignation

    Gdnf

    Sujet

    Synonyms: ATF-1

    Background: Glial Cell Line-Derived Neurotrophic Factor (GDNF) is a neurotrophic factor that is closely related to other neurotrophic factors, such as Neurturin, Persephin, and Artemin, by a common structural feature called the cysteine-knot. GDNF signals through a multicomponent system of receptors that includes RET and GFRα1-4, to promote dopamine uptake, survival and differentiation of neurons. Recombinant rat GDNF is a non-glycosylated homodimer, containing two 135 amino acid chains, with a total molecular weight of 30.1 kDa.

    UniProt

    Q07731

    Pathways

    Signalisation RTK, Synaptic Membrane, Tube Formation, Autophagy, Smooth Muscle Cell Migration
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