CCL5 Protein (AA 24-91)
Aperçu rapide pour CCL5 Protein (AA 24-91) (ABIN6952206)
Antigène
Voir toutes CCL5 ProtéinesType de proteíne
Activité biologique
Origine
Source
Application
Pureté
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Attributs du protein
- AA 24-91
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Séquence
- SPYSSDTTPC CFAYIARPLP RAHIKEYFYT SGKCSNPAVV FVTRKNRQVC ANPEKKWVRE YINSLEMS
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Attributs du produit
- Recombinant Human CCL5 (Rantes)
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niveau d'endotoxine
- <0.01 EU per 1μg of the protein by the LAL method
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Biological Activity Comment
- EC50 = 0.13 nM determined by Migration Assay in cells expressing recombinant CCR5
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
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Stock
- -20 °C,-80 °C
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Stockage commentaire
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12 months from date of receipt, -20 to -70 °C as supplied.
Suggest to use immediately after reconstitution
1 month at -20 to -70 °C under sterile conditions after reconstitution. -
Date de péremption
- 12 months
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- CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))
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Autre désignation
- CCL5 (Rantes)
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Sujet
- Regulated on Activation, Normal T cell Expressed and Secreted (RANTES) (CCL5) is a proinflammatory chemokine that induces migration and activation of leukocytes, as well as implication in HIV infection. It binds to cell surface receptors CCR1, CCR3, CCR4, and CCR5. Its biological effects on leukocyte activation and HIV infection displays dependence on concentration and on the binding of cell surface glycosaminoglycans.
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Poids moléculaire
- 7.851 kDa
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UniProt
- P13501
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration
Antigène
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