CD8 alpha Protein (Fc Tag)

N° du produit ABIN6964139

Protéine Recombinant CD8 alpha exprimée dans HEK-293 Cells.

Aperçu rapide pour CD8 alpha Protein (Fc Tag) (ABIN6964139)

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Détail du produit

Purification/Conjugué: Cette CD8 alpha protéine est marqué à la Fc Tag.

Séquence: CD8A(Ser22-Asp182)+hFc(Glu99-Ala330)

Attributs du produit: Tagged Protein: C-Human Fc tag

Purification: affinity purification

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Reconstitute with deionized water

Buffer: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.

Agent conservateur: Without preservative

Stock: -80 °C

Stockage commentaire: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Date de péremption: 12 months

Détail du antigène

Antigène: CD8 alpha (CD8A) (CD8a Molecule (CD8A))

Autre désignation: CD8A

Sujet: Synonymes: CD8, Leu2, p32
Description: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein.

Poids moléculaire: 43.23 kDa

UniProt: P01732

Pathways: TCR Signaling