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Survivin Protéine

Cette protéine Recombinant Survivin est exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7318193

Aperçu rapide pour Survivin Protéine (ABIN7318193)

Antigène

Voir toutes Survivin (BIRC5) Protéines
Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

Type de proteíne

Recombinant

Origine

  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Source

  • 9
  • 6
  • 3
  • 2
  • 1
Escherichia coli (E. coli)

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Fonction

    Recombinant Human Survivin/BIRC5 Protein

    Séquence

    Met 1-Asp142

    Attributs du produit

    Recombinant Human Baculoviral IAP Repeat-Containing Protein 5 is produced by our E.coli expression system and the target gene encoding Met1-Asp142 is expressed.

    niveau d'endotoxine

    < 1.0 EU per μg as determined by the LAL method.
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    Produit
    Système d'expression
    Conjugué
    Origin
    Prix à partir de
    Système d'expression HEK-293 Cells
    Conjugué His tag
    Origin Human
    Prix à partir de 12.620,45 €
    Système d'expression Cell-free protein synthesis (CFPS)
    Conjugué Strep Tag
    Origin Human
    Prix à partir de 20.480,57 €

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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of 20 mM Tris, 0.1M NaCl, pH 7.5.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    Survivin (BIRC5) (Baculoviral IAP Repeat-Containing 5 (BIRC5))

    Autre désignation

    Survivin/BIRC5

    Sujet

    Background: Baculoviral IAP Repeat-Containing Protein 5 (BIRC5) belongs to the IAP family. BIRC5 exists as a homodimer in the apo state and as a monomer in the CPC-bound state. BIRC5 contains one BIR repeat and is expressed only in fetal kidney and liver, and to lesser extent, lung and brain. BIRC5 functions as a multitasking protein that has dual roles in promoting cell proliferation and preventing apoptosis. BIRC5 is also a component of a chromosome passage protein complex (CPC), which is essential for chromosome alignment and segregation during mitosis and cytokinesis. BIRC5 acts as an important regulator of the localization of this complex.

    Synonym: Baculoviral IAP Repeat-Containing Protein 5, Apoptosis Inhibitor 4, Apoptosis Inhibitor Survivin, BIRC5, API4, IAP4

    Poids moléculaire

    20.4 kDa

    UniProt

    O15392

    Pathways

    Apoptose, Cycle Cellulaire, Nuclear Hormone Receptor Binding
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