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Cathepsin B Protein (CTSB) (His tag)

Protéine Recombinant Cathepsin B exprimée dans Human Cells.
N° du produit ABIN7318252

Aperçu rapide pour Cathepsin B Protein (CTSB) (His tag) (ABIN7318252)

Antigène

Voir toutes Cathepsin B (CTSB) Protéines
Cathepsin B (CTSB)

Type de proteíne

Recombinant

Origine

  • 15
  • 8
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Source

  • 10
  • 6
  • 5
  • 3
  • 2
  • 2
  • 2
  • 2
Human Cells

Pureté

> 95 % as determined by reducing SDS-PAGE.
  • Purification/Conjugué

    Cette Cathepsin B protéine est marqué à la His tag.

    Fonction

    Recombinant Human Cathepsin B/CTSB Protein (His Tag)

    Séquence

    Arg18-Ile339

    Attributs du produit

    Recombinant Human Cathepsin B is produced by our Mammalian expression system and the target gene encoding Arg18-Ile339 is expressed with a 6His tag at the C-terminus.

    niveau d'endotoxine

    < 1.0 EU per μg as determined by the LAL method.
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  • Restrictions

    For Research Use only
  • Format

    Frozen, Liquid

    Buffer

    Supplied as a 0.2 μm filtered solution of 20 mM TrisHCl, 150 mM NaCl, pH 8.0.

    Stock

    -20 °C

    Stockage commentaire

    Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
  • Antigène

    Cathepsin B (CTSB)

    Autre désignation

    Cathepsin B/CTSB

    Sujet

    Background: Cathepsin B is an enzymatic protein belonging to the peptidase (or protease) families. The protein encoded by this gene is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. At least five transcript variants encoding the same protein have been found for this gene. Cystatin-B / CSTB is an intracellular thiol proteinase inhibitor. Tightly binding reversible inhibitor of cathepsins L, H and B. Cystatin-B / CSTB is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. Cystatin-B / CSTB is also thought to play a role in protecting against the proteases leaking from lysosomes

    Synonym: Cathepsin B, APP Secretase, APPS, Cathepsin B1, CTSB, CPSB

    Poids moléculaire

    36.9 kDa

    UniProt

    P07858

    Pathways

    Activation of Innate immune Response, Toll-Like Receptors Cascades
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