Cathepsin Z Protein (CTSZ) (His tag)

N° du produit ABIN7319393

Cette protéine Recombinant Cathepsin Z est produite dans Human Cells.

Aperçu rapide pour Cathepsin Z Protein (CTSZ) (His tag) (ABIN7319393)

Antigène: Cathepsin Z (CTSZ)

Type de proteíne: Recombinant

Origine: Humain

Source: Human Cells

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Cathepsin Z protéine est marqué à la His tag.

Fonction: Recombinant Human Cathepsin Z Protein (His Tag)

Séquence: Gly24-Val303

Attributs du produit: Recombinant Human Cathepsin Z is produced by our Mammalian expression system and the target gene encoding Gly24-Val303 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of 20 mM HAc-NaAc, 150 mM NaCl, pH 4.0.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: Cathepsin Z (CTSZ)

Autre désignation: Cathepsin Z

Sujet:

Background: Cathepsin Z is a lysosomal cysteine proteinase and belongs to the peptidase C1 family. Human Cathepsin Z contains a singnal sequence, a propeptide and a mature chain. It exhibits bothcarboxy-monopeptidase and carboxy-dipeptidase activities. In contrast to cathepsin B, it does not act as an endopeptidase. Cathepsin Z is restricted to the cells of theimmune system, predominantly monocytes, macrophages and dendritic cells. It is expressed ubiquitously in cancer cell lines and primary tumors. Like other members of this family, Cathepsin Z may be involved in tumorigenesis.

Synonym: Cathepsin Z, Cathepsin P, Cathepsin X, CTSZ

Poids moléculaire: 32.5 kDa

UniProt: Q9UBR2

Pathways: Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones