CD72 Protein (AA 117-226) (His-TRX)

N° du produit ABIN7318196

Cette protéine Recombinant CD72 est produite dans Escherichia coli (E. coli).

Aperçu rapide pour CD72 Protein (AA 117-226) (His-TRX) (ABIN7318196)

Antigène: CD72 (CD72 Molecule (CD72))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 117-226

Purification/Conjugué: Cette CD72 protéine est marqué à la His-TRX.

Fonction: Recombinant Human CD72/Lyb-2 Protein (Trx&His)

Séquence: Arg117-Cys226

Attributs du produit: Recombinant Human B-Cell Differentiation Antigen CD72 is produced by our E.coli expression system and the target gene encoding Arg117-Cys226 is expressed with a Trx, 6His tag at the N-terminus.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU per μg of the protein as determined by the LAL method.

Biological Activity Comment: Not validated for activity

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween 80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CD72 (CD72 Molecule (CD72))

Autre désignation: CD72/Lyb-2

Sujet: B-Cell Differentiation Antigen CD72,CD72,Lyb-2,B-Cell Differentiation Antigen CD72 (CD72) is a single-pass type II membrane protein. CD72 exists as a disulfide-linked homodimer and contains one C-type lectin domain. CD72 is expressed on B lineage cells, NK cells, monocytes, dendritic cells, and mast cells. CD72 is a ligand for CD5. CD72 associates with CD5, interacts with PTPN6/SHP-1 and plays a role in B-cell proliferation and differentiation. CD72 associates with CD79A in the B cell antigen receptor (BCR) complex following antigen stimulation and dampens BCR signaling through interactions with the phosphatase SHP-1.

Poids moléculaire:

Calculated MW: 30.6 kDa

Observed MW: 26-35 kDa

ID gène: 971

UniProt: P21854

Pathways: BCR Signaling