FGF7 Protéine
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- Antigène Voir toutes FGF7 Protéines
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Fonction
- Recombinant Human FGF-7/KGF Protein (Active)
- Séquence
- Cys32-Thr194
- Attributs du produit
- Recombinant Human Fibroblast Growth Factor 7/Keratinocyte growth factor is produced by our E.coli expression system and the target gene encoding Cys32-Thr194 is expressed.
- Pureté
- > 95 % as determined by reducing SDS-PAGE.
- niveau d'endotoxine
- < 1.0 EU per μg as determined by the LAL method.
- Biological Activity Comment
- Immobilized Human KGF at 2μg/ml(100 μl/well) can bind Human FGF R3-Fc(Cat: PKSH033678). The ED50 of Human KGF is 0.788 ug/ml .
- Top Product
- Discover our top product FGF7 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from a 0.2 μm filtered solution of 20 mM PB, pH 8.0,l50 mM NaCl.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Antigène
- FGF7 (Fibroblast Growth Factor 7 (FGF7))
- Autre désignation
- FGF-7/KGF (FGF7 Produits)
- Synonymes
- HBGF-7 Protein, KGF Protein, Kgf Protein, kgf Protein, FGF-7 Protein, fgf7 Protein, fibroblast growth factor 7 Protein, fibroblast growth factor 7 L homeolog Protein, FGF7 Protein, Fgf7 Protein, fgf7 Protein, fgf7.L Protein
- Sujet
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Background: Fibroblast growth factor 7 (FGF7) is a secreted protein which is mainly located in epithelial cells and belongs to the heparin-binding growth factors family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF7 is a potent epithelial cell-specific growth factor, whose mitogenic activity is predominantly exhibited in keratinocytes but not in fibroblasts and endothelial cells. It is possible major paracrine effector of normal epithelial cell proliferation.
Synonym: Fibroblast growth factor 7,FGF-7,Heparin-binding growth factor 7,HBGF-7,Keratinocyte growth factor,FGF7,KGF
- Poids moléculaire
- 19.1 kDa
- UniProt
- P21781
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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