GZMB Protein (His tag)

N° du produit ABIN7320540

Protéine Recombinant GZMB exprimée dans Human Cells.

Aperçu rapide pour GZMB Protein (His tag) (ABIN7320540)

Antigène: GZMB (Granzyme B (GZMB))

Type de proteíne: Recombinant

Origine: Souris

Source: Human Cells

Pureté: > 85 % as determined by SDS-PAGE

Détail du produit

Purification/Conjugué: Cette GZMB protéine est marqué à la His tag.

Fonction: Recombinant Mouse Granzyme B(G,H)/GZMB Protein (His Tag)

Séquence: Gly19-Ser247

Attributs du produit: Recombinant Mouse Granzyme B is produced by our Mammalian expression system and the target gene encoding Gly19-Ser247 is expressed with a 6His tag at the C-terminus.

niveau d'endotoxine: < 1.0 EU per μg as determined by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Frozen, Liquid

Buffer: Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C

Stockage commentaire: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Détail du antigène

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B/GZMB

Sujet:

Background: Granzyme B(GZMB) contains 1 peptidase S1 domain and belongs to the peptidase S1 family. This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp and seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. The protein cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Synonym: Granzyme B(G,H),CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1

Poids moléculaire: 26.5 kDa

UniProt: P04187

Pathways: Apoptose, Caspase Cascade in Apoptosis