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SNCA Protéine

Protéine Recombinant SNCA exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7320688

Aperçu rapide pour SNCA Protéine (ABIN7320688)

Antigène

Voir toutes SNCA Protéines
SNCA (Synuclein, alpha (SNCA))

Type de proteíne

Recombinant

Origine

  • 33
  • 8
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Souris

Source

  • 31
  • 13
  • 5
  • 2
  • 2
Escherichia coli (E. coli)

Pureté

> 95 % as determined by SDS-PAGE
  • Fonction

    Recombinant Mouse α-Synuclein/SNCA Protein

    Séquence

    Met1-Ala140

    Attributs du produit

    Recombinant Mouse alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.

    niveau d'endotoxine

    < 1.0 EU per μg as determined by the LAL method.
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    Produit
    Système d'expression
    Conjugué
    Origin
    Prix à partir de
    Système d'expression HEK-293 Cells
    Conjugué His tag
    Origin Mouse
    Prix à partir de 13.711,36 €
    Système d'expression Cell-free protein synthesis (CFPS)
    Conjugué Strep Tag
    Origin Mouse
    Prix à partir de 15.754,29 €

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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Please refer to the printed manual for detailed information.

    Buffer

    Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

    Stock

    4 °C,-20 °C,-80 °C

    Stockage commentaire

    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
  • Antigène

    SNCA (Synuclein, alpha (SNCA))

    Autre désignation

    alpha-Synuclein/SNCA

    Sujet

    Background: Alpha-Synuclein (SNCA) is a member of the Synuclein family. SNCA is expressed principally in brain but also expressed in low concentrations in all tissues except liver. SNCA interacts with UCHL1, Phospholipase D and histones. SNCA can include beta- and gamma-synuclein. In addition, SNCA is an important regulatory component of vesicular transport in neuronal cells. It has been suggested that SNCA is related to the pathogenesis of Parkinson's Disease and neurodegenerative disorders. Defects in SNCA will lead to Dementia Lewy Body (DLB).

    Synonym: Alpha-synuclein, Non-A beta component of AD amyloid, Non-A4 component of amyloid precursor, NACP, Snca

    Poids moléculaire

    14.5 kDa

    UniProt

    O55042

    Pathways

    Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Platelet-derived growth Factor Receptor Signaling, Negative Regulation of Transporter Activity, Regulation of long-term Neuronal Synaptic Plasticity
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