CD80 Protein (CD80) (AA 38-246) (His tag)

N° du produit ABIN7273895

Protéine Recombinant CD80 exprimée dans HEK-293 Cells.

Aperçu rapide pour CD80 Protein (CD80) (AA 38-246) (His tag) (ABIN7273895)

Antigène: CD80

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Souris

Source: HEK-293 Cells

Pureté: > 95 % as determined by Bis-Tris PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 38-246

Purification/Conjugué: Cette CD80 protéine est marqué à la His tag.

Fonction: Mouse B7-1/CD80 Protein

Séquence: Val38-Asn246

Attributs du produit: Recombinant Mouse B7-1/CD80 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Val38-Asn246.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1 EU per μg by the LAL method.

Biological Activity Comment: Mouse B7-1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.,The purity of Mouse B7-1 is greater than 95% as determined by SEC-HPLC.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD80

Autre désignation: B7-1

Sujet: Cluster of differentiation 80 (also CD80 and B7-1) is a protein found on dendritic cells, activated B cells and monocytes that provides a costimulatory signal necessary for T cell activation and survival. It is the ligand for two different proteins on the T cell surface: CD28 and CTLA-4.

Poids moléculaire: 24.6 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.

UniProt: Q00609

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints