Ephrin B2 Protein (EFNB2) (AA 28-229) (Fc Tag)

N° du produit ABIN7274531

Protéine Recombinant Ephrin B2 exprimée dans HEK-293 Cells.

Aperçu rapide pour Ephrin B2 Protein (EFNB2) (AA 28-229) (Fc Tag) (ABIN7274531)

Antigène: Ephrin B2 (EFNB2)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Détail du produit

Attributs du protein: AA 28-229

Purification/Conjugué: Cette Ephrin B2 protéine est marqué à la Fc Tag.

Fonction: Human Ephrin-B2/EFNB2 Protein

Séquence: Ile28-Ala229

Attributs du produit: Recombinant Human Ephrin-B2/EFNB2 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ile28-Ala229.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: Ephrin B2 (EFNB2)

Autre désignation: Ephrin-B2

Sujet: Ephrin-B2 controls platelet-derived growth factor receptor β (PDGFRβ) distribution in the VSMC plasma membrane, endocytosis, and signaling in a fashion that is highly distinct from its role in the endothelium. Ephrin-B2 is an important regulator of PDGFRβ endocytosis and thereby acts as a molecular switch controlling the downstream signaling activity of this receptor in mural cells.

Poids moléculaire: 49 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_004084

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation