Ephrin B2 Protein (EFNB2) (AA 29-227) (Fc Tag,His tag)

N° du produit ABIN1691758

Détail du produit

Antigène: Ephrin B2 (EFNB2)

Type de proteíne: Recombinant

Attributs du protein: AA 29-227

Origine: Souris

Source: Human Cells

Purification/Conjugué: Cette Ephrin B2 protéine est marqué à la Fc Tag,His tag.

Fonction: Recombinant Mouse Ephrin-B2/EFNB2 (C-Fc-6His)

Séquence: RSIVLEPIYW NSSNSKFLPG QGLVLYPQIG DKLDIICPKV DSKTVGQYEY YKVYMVDKDQ ADRCTIKKEN TPLLNCARPD QDVKFTIKFQ EFSPNLWGLE FQKNKDYYII STSNGSLEGL DNQEGGVCQT RAMKILMKVG QDASSAGSAR NHGPTRRPEL EAGTNGRSST TSPFVKPNPG SSTDGNSAGH SGNNLLGSEV DDIEGRMDEP KSCDKTHTCP PCPAPELLGG PSVFLFPPKP KDTLMISRTP EVTCVVVDVS HEDPEVKFNW YVDGVEVHNA KTKPREEQYN STYRVVSVLT VLHQDWLNGK EYKCKVSNKA LPAPIEKTIS KAKGQPREPQ VYTLPPSREE MTKNQVSLTC LVKGFYPSDI AVEWESNGQP ENNYKTTPPV LDSDGSFFLY SKLTVDKSRW QQGNVFSCSV MHEALHNHYT QKSLSLSPGK HHHHHH

Attributs du produit:

Recombinant Mouse Ephrin-B2/EFNB2 (C-Fc-6His)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Conseil sur la manipulation: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Stock: 4 °C/-20 °C/-80 °C

Stockage commentaire: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Détail du antigène

Antigène: Ephrin B2 (EFNB2)

Autre désignation: Ephrin-B2/Efnb2 (EFNB2 Produits)

Synonymes: EFNB2 Protein, efnb2 Protein, ephrin-B2 Protein, htkl Protein, eplg5 Protein, htk-l Protein, lerk5 Protein, ephrinB2 Protein, efnb2a Protein, MGC68890 Protein, efnb2b Protein, ELF-2 Protein, Epl5 Protein, Eplg5 Protein, Htk-L Protein, LERK-5 Protein, Lerk5 Protein, NLERK-1 Protein, EPLG5 Protein, HTKL Protein, LERK5 Protein, ephrin B2 Protein, ephrin-B2 precursor Protein, ephrin B2 L homeolog Protein, ephrin B2 S homeolog Protein, EFNB2 Protein, efnb2 Protein, efnb2.L Protein, efnb2.S Protein, Efnb2 Protein

Sujet: Recombinant Mouse Ephrin-B2/Efnb2 produced by transfected human cells is a secreted protein with sequence (Arg29-Glu227) of Mouse Ephrin-B2 fused with a FC-6His tag at the C-terminus.
Ephrin-B2 is a single-pass type I membrane protein and it contains 1 ephrin RBD (ephrin receptor-binding) domain. Ephrin-B2 belongs to the ephrin (EPH) family and it is cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. The ephrins and EPH-related receptors contain the largest subfamily of receptor protein-tyrosine kinases and have been associated with mediating developmental events, particularly in the nervous system and in erythropoiesis. Based upon their structures and sequence relationships, ephrins are allocated into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. It also binds to receptor tyrosine kinase including EPHA4, EPHA3 and EPHB4 and together with EPHB4 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration.

Poids moléculaire: 49.6 kDa

UniProt: P52800

Pathways: Signalisation RTK, Regulation of Muscle Cell Differentiation