IL-18 Protein (AA 37-193) (Biotin)
Aperçu rapide pour IL-18 Protein (AA 37-193) (Biotin) (ABIN7274881)
Antigène
Voir toutes IL-18 (IL18) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 37-193
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Purification/Conjugué
- Cette IL-18 protéine est marqué à la Biotin.
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Fonction
- Biotinylated Human IL-18 Protein (Primary Amine Labeling)
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Séquence
- Tyr37-Asp193
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Attributs du produit
- Recombinant Biotinylated Human IL-18 Protein (Primary Amine Labeling) is expressed from E.coli without tag.It contains Tyr37-Asp193.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-18BP, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-18, No Tag with the EC50 of 24.2ng/ml determined by ELISA. See testing image for detail.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Supplied as 0.22μm filtered solution in 20 mM PB, 250 mM NaCl, 50 mM L-arginine ( pH 7.4).
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Stock
- -80 °C
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Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- IL-18 (IL18) (Interleukin 18 (IL18))
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Autre désignation
- IL-18
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Sujet
- Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naive T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation.
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Poids moléculaire
- 18.2 kDa same as Tris-Bis PAGE result.
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UniProt
- Q14116
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Pathways
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
Antigène
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