IL-7 Protein (AA 26-177)
Aperçu rapide pour IL-7 Protein (AA 26-177) (ABIN7274963)
Antigène
Voir toutes IL-7 (IL7) ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 26-177
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Fonction
- Human IL-7 Protein
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Séquence
- Asp26-His177
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Attributs du produit
- Recombinant Human IL-7 Protein is expressed from E.coli without tag.It contains Asp26-His177.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 0.1 EU per μg by the LAL method.
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Biological Activity Comment
- Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). The affinity constant of 7.15 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- IL-7 (IL7) (Interleukin 7 (IL7))
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Autre désignation
- IL-7
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Sujet
- Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor.
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Poids moléculaire
- 17.5 kDa same as Tris-Bis PAGE result.
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UniProt
- P13232
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Pathways
- Signalistation JAK/STAT
Antigène
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