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IL-7 Protein (AA 26-177)

Protéine Recombinant IL-7 exprimée dans Escherichia coli (E. coli).
N° du produit ABIN7274963

Aperçu rapide pour IL-7 Protein (AA 26-177) (ABIN7274963)

Antigène

Voir toutes IL-7 (IL7) Protéines
IL-7 (IL7) (Interleukin 7 (IL7))

Type de proteíne

Recombinant

Origine

  • 23
  • 14
  • 6
  • 1
  • 1
  • 1
  • 1
Humain

Source

  • 22
  • 10
  • 5
  • 3
  • 2
  • 2
  • 2
  • 1
Escherichia coli (E. coli)

Pureté

> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
  • Attributs du protein

    AA 26-177

    Fonction

    Human IL-7 Protein

    Séquence

    Asp26-His177

    Attributs du produit

    Recombinant Human IL-7 Protein is expressed from E.coli without tag.It contains Asp26-His177.

    Stérilité

    0.22 μm filtered

    niveau d'endotoxine

    Less than 0.1 EU per μg by the LAL method.

    Biological Activity Comment

    Immobilized Human IL-7 at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human IL-7R alpha, hFc Tag with the EC50 of 16.2ng/ml determined by ELISA (QC tested). The affinity constant of 7.15 nM as determined in SPR assay (Biacore T200). See testing image for detail.
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  • Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

    Buffer

    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

    Stock

    -20 °C,-80 °C

    Stockage commentaire

    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    IL-7 (IL7) (Interleukin 7 (IL7))

    Autre désignation

    IL-7

    Sujet

    Interleukin-7 (IL7) plays a nonredundant role in T cell survival and homeostasis, which is illustrated in the severe T cell lymphopenia of IL7-deficient mice, or demonstrated in animals or humans that lack expression of either the IL7Rα or γ c chain, the two subunits that constitute the functional IL7 receptor.

    Poids moléculaire

    17.5 kDa same as Tris-Bis PAGE result.

    UniProt

    P13232

    Pathways

    Signalistation JAK/STAT
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