Midkine Protein (AA 21-143) (His-Avi Tag)
Aperçu rapide pour Midkine Protein (AA 21-143) (His-Avi Tag) (ABIN7275259)
Antigène
Voir toutes Midkine (MDK) ProtéinesType de proteíne
Activité biologique
Origine
Source
Pureté
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Attributs du protein
- AA 21-143
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Purification/Conjugué
- Cette Midkine protéine est marqué à la His-Avi Tag.
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Fonction
- Non-biotinylated Human Midkine Protein
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Séquence
- Val21-Asp143
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Attributs du produit
- Recombinant Human Midkine Protein is expressed from E.coli with His tag and Avi Tag at the N-Terminus.It contains Val21-Asp143.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 1 EU per μg by the LAL method.
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Biological Activity Comment
- Human Midkine on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 μg or less, at 1 mg/mL for 500 μg or 1 mg lyophilized powder. Do not mix by vortex or vigorous shaking.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3 months after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- Midkine (MDK) (Midkine (Neurite Growth-Promoting Factor 2) (MDK))
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Autre désignation
- Midkine
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Sujet
- Midkine is a heparin-binding growth factor, originally reported as the product of a retinoic acid-responsive gene during embryogenesis, but currently viewed as a multifaceted factor contributing to both normal tissue homeostasis and disease development. Midkine is abnormally expressed at high levels in various human malignancies and acts as a mediator for the acquisition of critical hallmarks of cancer, including cell growth, survival, metastasis, migration, and angiogenesis.
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Poids moléculaire
- 16.46 kDa same as Bis-Tris PAGE result.
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UniProt
- P21741
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Pathways
- Signalisation RTK, M Phase, Skeletal Muscle Fiber Development
Antigène
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