NOG Protein (AA 28-232)
Aperçu rapide pour NOG Protein (AA 28-232) (ABIN7275358)
Antigène
Voir toutes NOG ProtéinesType de proteíne
Origine
Source
Pureté
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Attributs du protein
- AA 28-232
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Fonction
- Human Noggin Protein
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Séquence
- Gln28-Cys232
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Attributs du produit
- Recombinant Human Noggin Protein is expressed from CHO without tag.It contains Gln28-Cys232.
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Stérilité
- 0.22 μm filtered
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niveau d'endotoxine
- Less than 0.05 EU per μg by the LAL method.
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Noggin (NOG) (AA 20-232) (Active) protein
NOG Origine: Souris Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) (AA 28-232) (Active) proteinNOG Origine: Humain Hôte: CHO Cells Recombinant > 95 % as analyzed by SDS-PAGE. Active
Noggin (NOG) protein (His tag)NOG Origine: Souris Hôte: Human Cells Recombinant > 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (His-IF2DI Tag)NOG Origine: Souris Hôte: Escherichia coli (E. coli) Recombinant Greater than 90 % as determined by SDS-PAGE. WB, ELISA
Noggin (NOG) (AA 28-232) protein (GST tag)NOG Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AA, AP
Noggin (NOG) protein (Fc Tag)NOG Origine: Humain Hôte: HEK-293 Cells Recombinant Greater than 95 % as determined by reducing SDS-PAGE.
Noggin (NOG) (AA 28-232) protein (Fc Tag)NOG Origine: Humain Hôte: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
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Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
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Stock
- -20 °C,-80 °C
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Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
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Date de péremption
- 12 months
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- NOG (Noggin (NOG))
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Autre désignation
- Noggin
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Sujet
- Noggin is an antagonist of bone morphogenetic proteins (BMP), being indispensable for certain developmental events.Noggin expression positively correlated with EGFR expression in both GC cell line models and The Cancer Genome Atlas human GC cohort. Targeting EGFR and its downstream pathways diminished cell proliferation which was promoted by Noggin. Noggin promotes the proliferation of GC cells by upregulating EGFR and enhancing a vicious circle formed by β-catenin, EGFR, ERK and Akt.
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Poids moléculaire
- 23.05 kDa. Due to glycosylation, the protein migrates to 30-36 kDa based on Tris-Bis PAGE result.
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UniProt
- Q13253
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Pathways
- Stem Cell Maintenance, Tube Formation
Antigène
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