BDNF Protéine

N° du produit ABIN7488780

Protéine Recombinant BDNF exprimée dans HEK-293 Cells.

Aperçu rapide pour BDNF Protéine (ABIN7488780)

Antigène: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Pureté: 95 %

Classe de qualité: Premium grade

Détail du produit

Fonction: Human BDNF / Abrineurin Protein, premium grade

Séquence: His 129 - Arg 247

Attributs du produit: Human BDNF, premium grade is expressed from human 293 cells (HEK293). It contains AA His 129 - Arg 247 (Accession # P23560-1).

niveau d'endotoxine: 0.01 EU per μg

Information d'application

Commentaires:

This protein carries no "tag". () The protein has a calculated MW of 13.5 kDa. The protein migrates as 15-17 kDa and 19 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: BDNF (Brain-Derived Neurotrophic Factor (BDNF))

Autre désignation: BDNF

Sujet: Brain-derived neurotrophic factor (BDNF) along with nerve growth factor (NGF), neurotrophin-3 (NT-3), and neurotrophin-4/5 (NT-4/5) are members of the neurotrophin family of trophic factors. The neurotrophins play essential roles in the development, survival, and function of a wide range of neurons in both the peripheral and central nervous systems. The neurotrophins interact with two cell surface receptors, the low affinity P75 receptor and the Trk family of high affinity tyrosine kinase receptors. NGF preferentially binds TrkA, BDNF and NT4/5 bind TrkB, and NT-3 binds TrkC (and TrkA to a lesser extent).

Poids moléculaire: 13.5 kDa

Pathways: Signalisation RTK, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity