Glucagon Receptor Protein-VLP (GCGR)

N° du produit ABIN7489074

Cette protéine VLP Glucagon Receptor est produite dans HEK-293 Cells.

Aperçu rapide pour Glucagon Receptor Protein-VLP (GCGR) (ABIN7489074)

Antigène: Glucagon Receptor (GCGR)

Type de proteíne: VLP

Origine: Humain

Source: HEK-293 Cells

Détail du produit

Fonction: Human GCGR / Glucagon receptor Full Length Protein (VLP)

Séquence: Ala 26 - Asn 432

Attributs du produit: Human GCGR Full Length Protein (VLP) is expressed from human 293 cells (HEK293). It contains AA Ala 26 - Asn 432 (Accession # P47871-1).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, Arginine, pH 7.4

Stock: -80 °C

Stockage commentaire: -70°C

Détail du antigène

Antigène: Glucagon Receptor (GCGR)

Autre désignation: GCGR

Sujet: The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of  type 2 diabetes mellitus (T2DM) . The ever increasing prevalence of type 2 diabetes mellitus in the developed and developing nations calls for the introduction of new and more effective treatments. Glucagon receptor (GCGR) antagonists are highly validated in preclinical models of T2DM and thus have the potential to be developed as a new therapy.

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process