Glucagon Receptor Protein (GCGR) (AA 26-136) (His tag)

N° du produit ABIN7013755

Détail du produit

Antigène: Glucagon Receptor (GCGR)

Type de proteíne: Recombinant

Attributs du protein: AA 26-136

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Glucagon Receptor protéine est marqué à la His tag.

Attributs du produit: Human GCGR / Glucagon receptor Protein, His Tag (MALS verified)

Pureté: >90 % as determined by SDS-PAGE.

niveau d'endotoxine: Less than 0.1 EU per μg by the LAL method.

Information d'application

Indications d'application: MALS verified

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Détail du antigène

Antigène: Glucagon Receptor (GCGR)

Autre désignation: GCGR (GCGR Produits)

Synonymes: GCGR Protein, GGR Protein, GR Protein, glucagon receptor Protein, GCGR Protein, Gcgr Protein

Sujet: G-protein coupled receptor for glucagon that plays a central role in the regulation of blood glucose levels and glucose homeostasis. Regulates the rate of hepatic glucose production by promoting glycogen hydrolysis and gluconeogenesis. Plays an important role in mediating the responses to fasting. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Promotes activation of adenylate cyclase. Besides, plays a role in signaling via a phosphatidylinositol-calcium second messenger system.

Poids moléculaire: 14.9 kDa

Pathways: Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process