Mesothelin Protein (MSLN) (Fc Tag)
Aperçu rapide pour Mesothelin Protein (MSLN) (Fc Tag) (ABIN7482581)
Antigène
Voir toutes Mesothelin (MSLN) ProtéinesType de proteíne
Origine
Source
Pureté
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Purification/Conjugué
- Cette Mesothelin protéine est marqué à la Fc Tag.
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Fonction
- Mouse Mesothelin / MSLN Protein, Fc Tag
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Séquence
- Asp 298 - Ser 600
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Attributs du produit
- Mouse Mesothelin Protein, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Asp 298 - Ser 600 (Accession # Q61468-1).
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niveau d'endotoxine
- 1.0 EU per μg
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Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)
MSLN Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc-Avi Tag,Biotin)MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (Fc Tag)MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag)MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 406-690) protein (His tag)MSLN Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (mFc-His Tag)MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining. WB
Mesothelin (MSLN) (AA 406-690) protein (His tag,Biotin)MSLN Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 296-580) protein (His-Avi Tag,Biotin)MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Mesothelin (MSLN) (AA 1-375) protein (His tag)custom-made MSLN Origine: Souris Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
Mesothelin (MSLN) (AA 1-375) protein (His tag)custom-made MSLN Origine: Humain Hôte: HEK-293 Cells Recombinant > 90 % as determined by Bis-Tris PAGE, anti-tag ELISA, Western Blot and analytical SEC (HPLC)
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Commentaires
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This protein carries a human IgG1 Fc tag at the C-terminus. (Fc) The protein has a calculated MW of 60.6 kDa. The protein migrates as 67-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- Mesothelin (MSLN)
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Autre désignation
- Mesothelin
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Sujet
- Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
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Poids moléculaire
- 60.6 kDa
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Pathways
- EGFR Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, cAMP Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process
Antigène
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