Interferon gamma Protein (IFNG) (AA 24-166) (His tag)

N° du produit ABIN7505577

Protéine Recombinant Interferon gamma exprimée dans HEK-293 Cells.

Aperçu rapide pour Interferon gamma Protein (IFNG) (AA 24-166) (His tag) (ABIN7505577)

Antigène: Interferon gamma (IFNG)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Application: Immunogen (Imm)

Pureté: > 90 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 24-166

Purification/Conjugué: Cette Interferon gamma protéine est marqué à la His tag.

Fonction: Recombinant Human Interferon γ/IFNG Protein

Séquence: Gln24-Gln166

Attributs du produit: Recombinant Human Interferon gamma is produced by our Mammalian expression system and the target gene encoding Gln24-Gln166 is expressed.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: < 1.0 EU/mg of the protein as determined by the LAL method

Biological Activity Comment: Not validated for activity

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with 5 % Trehalose and 5 % Mannitol.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Interferon gamma (IFNG)

Autre désignation: Interferon gamma

Sujet: IFN-Gamma,IFNG,Immune Interferon,Interferon Gamma,IFNγ is the major interferon produced by mitogenically or antigenically stimulated lymphocytes. It is structurally different from type I interferon and its major activity is immunoregulation. It has been implicated in the expression of class II histocompatibility antigens in cells that do not normally produce them, leading to autoimmune disease. Interferon gamma is produced mainly byT-cells and natural killer cells activated by antigens, mitogens, or alloantigens. It is produced by lymphocytes expressing the surface antigens CD4 and CD8. IFNγ synthesis is induced by IL-2, FGF-basic, and EGF.

Poids moléculaire:

Calculated MW: 16.8 kDa

Observed MW: 16 & 20-25 kDa

ID gène: 3458

UniProt: P01579

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy