FGF3 Protéine

N° du produit ABIN7535418

Détail du produit

Antigène: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Fonction: Recombinant Human FGF-3 Protein

Séquence: DAGGRGGVYE HLGGAPRRRK LYCATKYHLQ LHPSGRVNGS LENSAYSILE ITAVEVGIVA IRGLFSGRYL AMNKRGRLYA SEHYSAECEF VERIHELGYN TYASRLYRTV SSTPGARRQP SAERLWYVSV NGKGRPRRGF KTRRTQKSSL FLPRVLDHRD HEMVRQLQSG LPRPPGKGVQ PRRRR

Specificité: Asp28-Arg212(N-Met)

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 25 mM Tris,1M NaCl,1 mM TCEP, pH 8.0

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for long term.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: FGF3 (Fibroblast Growth Factor 3 (FGF3))

Autre désignation: FGF-3 (FGF3 Produits)

Synonymes: HBGF-3 Protein, INT2 Protein, Int2 Protein, Fgf-3 Protein, Int-2 Protein, Int-P Protein, INT-2 Protein, XFGF-3 Protein, fgf3-A Protein, xfgf3 Protein, FGF-3 Protein, id:ibd5006 Protein, fibroblast growth factor 3 Protein, fibroblast growth factor 3 L homeolog Protein, FGF3 Protein, Fgf3 Protein, fgf3.L Protein, fgf3 Protein

Sujet:

Description: Fibroblast Growth Factor 3 (FGF-3) belongs to the large FGF family which has at least 23 members. All FGF family members are heparin-binding growth factors with a core 120 amino acid (aa) FGF domain that allows for a common tertiary structure. FGFs are expressed during embryonic development and in restricted adult tissues. They act on cells of mesodermal and neuroectodermal origin to regulate diverse physiologic functions including angiogenesis, cell growth, pattern formation, embryonic development, metabolic regulation, cell migration, neurotrophic effects and tissue repair. Signaling receptors for FGFs are type I transmembrane receptor tyrosine kinases belonging to the Ig superfamily. Four distinct but related classes of FGF receptors, FGF R1, 2, 3, and 4, exist. Through alternative splicing, multiple isoforms for FGF R1, 2 and 3, with distinct ligand recognition profiles, are also generated.

Name: FGF3,HBGF-3,INT2

ID gène: 2248

UniProt: P11487

Pathways: Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway