Oncostatin M Protein (OSM) (His tag)

N° du produit ABIN7536079

Protéine Recombinant Oncostatin M exprimée dans HEK-293 Cells.

Aperçu rapide pour Oncostatin M Protein (OSM) (His tag) (ABIN7536079)

Antigène: Oncostatin M (OSM)

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Pureté: > 97 % by SDS-PAGE.

Détail du produit

Purification/Conjugué: Cette Oncostatin M protéine est marqué à la His tag.

Fonction: Recombinant Mouse Oncostatin-M/OSM Protein

Séquence: MQTRLLRTLL SLTLSLLILS MALANRGCSN SSSQLLSQLQ NQANLTGNTE SLLEPYIRLQ NLNTPDLRAA CTQHSVAFPS EDTLRQLSKP HFLSTVYTTL DRVLYQLDAL RQKFLKTPAF PKLDSARHNI LGIRNNVFCM ARLLNHSLEI PEPTQTDSGA SRSTTTPDVF NTKIGSCGFL WGYHRFMGSV GRVFREWDDG STRSRR

Specificité: Met 1-Arg 206

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: Oncostatin M (OSM)

Autre désignation: Oncostatin-M/OSM

Sujet:

Description: OSM is a pleiotropic cytokine that initiates its biological activities by binding to specific cell surface receptors. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration.

Name: OncoM,OSM

ID gène: 18413

UniProt: P53347

Pathways: Signalistation JAK/STAT, Negative Regulation of Hormone Secretion